
Advancements in basic and translational cancer research continue to fuel development of multi-pronged therapeutic strategies targeting established and emerging hallmarks of cancer (see diagram right). Your aim may be to investigate cancer’s genetic origins, establish the mechanism of action or clinical implications of tumor biomarkers, or develop a targeted pharmaceutical, biotherapeutic, or cellular therapy. Enzo’s diverse scientific expertise and manufacturing capabilities facilitate those aims, offering an extensive portfolio of products that serve the equally broad demands of the cancer research and translational discovery markets. Our continuing efforts to develop innovative platforms and research tools are focused on enabling a future with more hope, more collaboration, more discovery, and less disease.
Established hallmarks (blue text), emerging hallmarks (red), and enabling characteristics (green) of cancer, as defined by Hanahan and Weinberg. Cell, Volume 144, Issue 5, 646-674, 4 March 2011.
Programmed Cell Death
Cyto-ID® Autophagy Detection Kit
Lyso-ID Detection Kit
p62 & NBR1 ELISAs
ProteoStat® Aggresome Detection Kit
Autophagy Compound Library
LC3 Antibodies
Caspase Activity Assays
CELLestial® Apoptosis/Necrosis Detection Kit
Nuclear-ID® Chromatin Condensation Kit
M30 & M65 Epithelial Cell Death ELISAs
Cytochrome C , p53 , Survivin & BAX, XIAP & Bcl-2 ELISAs
Cell Cycle Analysis
Nuclear-ID® Cell Viability Reagents
Nuclear-ID® Cell Cycle Analysis Kits
Nucleolar-ID® Detection Kits
CDK Inhibitors & Cyclin Antibodies
p21 & p27Kip1 ELISAs
Kinase Inhibitor Library
Toxicity & Chemoresistance
eFluxx-ID® Multidrug Resistance Assay Kits
Toxicity Compound Libraries
Lyso-ID® Red Cytotoxicity Kit
Mito-ID® Membrane Potential Cytotoxicity Kit
Natural Products Compound Library
FDA Approved Compound Library
Microcystin ELISA & Standards
Tumor Immunology
CD40, TRAIL, and FasL Mega™ Ligands
TNF Superfamily Antibodies & Proteins
PGE2, TXB2, LTB4 & COX ELISA Kits
Human & Mouse Cytokine ELISA Kits
TLR Signaling Antibodies & Ligands
NF-kB p65 ELISA Kit
Epigenetic Regulation
Chemilum de Lys HDAC & Sirtuin Assay
Fluor de Lys® HDAC & Sirtuin Assays
LSD1 Fluorimetric Drug Discovery Kit
Active HDAC & SIRT Enzymes
Epigenetics Compound Library
Ubiquitinylation
SUMOylation
Oncogenic Signaling
Leading Light™ Wnt Reporter Assay
Dkk-1, GSK-3β, & β-catenin ELISA Kits
Wnt Compound Library
Akt, PKA & PKC Kinase Activity Kits
cAMP/cGMP ELISA Kits
PI3K/Akt/mTOR Antibodies & Modulators
MAP Kinase ELISAs & Antibodies
Ras/Rho/Rac1/Rap1 Activation Kits
Kinase & Phosphatase Inhibitor Compound Libraries
Oxidative Stress & DNA Damage
DNA Damage (8-OHdG) ELISA
Stressgen® HSP ELISA Kits & Antibodies
Total ROS/Superoxide Detection Kits
ROS/RNS Detection Kit
Mito-ID® MMP Assay Kits
NO Detection Kits
Heme Oxygenase ELISAs
REDOX Compound Library
Gene Expression & Copy Number
aCGH Labeling Kits for Oligo Arrays
BioArray® Low Input RNA Amplification Kit
Fluorescent dUTPs & Nick Translation System
BioProbe® Labeling & Detection Systems
Pathogene® HPV In Situ Screening Assay
Tumor Invasion & Angiogenesis
HIF-1α and HIF-2α Antibodies & Modulators
Angiogenesis
Cell Adhesion MMP Drug Discovery Assays
Serine Protease ELISAs & Antibodies
VEGF & VEGFR Detection & Inhibition
NGAL ELISA Kits
Protease Inhibitor Compound Library
Cyto-ID® Long-term Tracer Kits
Metabolism
Adiponectin Protein & ELISA Kit
GLP-1 Antibodies
Human, Mouse & Rat Leptin ELISAs
Insulin Receptor & IGF Antibodies
Fluor de Lys® SIRT5 Assay Kits
Could A Little Ginger Help Fight Cancer?
2013 April 5 | Tags:
Autophagy,
Cancer,
Epigenetics,
Proteasome
Circumventing drug resistance in breast cancer cells by down-regulating the Wnt/β-catenin pathway.
2012 November 16 | Tags:
Cancer,
Screening,
Toxicology
The Phytochemical Sulforaphane Appears to Prevent Cancer through Two Distinct Epigenetic Mechanisms.
2012 September 21 | Tags:
Cancer,
Epigentics
Salvaging impaired inflammasome function in elderly mice with flu.
2012 July 27 | Tags:
Cancer,
Inflammation
Building better dendritic cells for cancer vaccination.
2012 July 13 | Tags:
Cancer
Resveratrol's metabolic effects include inhibition of PDE 4 and activation of sirtuin 1.
2012 April 13 | Tags:
Cancer,
Epigenetics,
Inflammation,
Metabolism,
Neuroscience