Our panel of fluorescence-based live cell assays is designed to help assess the impact of toxic agents on overall cell function. Our assays and probes have been developed to produce dyes that are sensitive, specific, and convenient. This offers increased photostability, eliminating non-specific dye-associated artifacts to reduce false positives, and compatibility with common dyes and fluorescent markers for multiplexing analysis. Our dyes are optimized for the most demanding imaging applications which allows their versatility to be used on a number of different platforms including, microplate-based high content screening, flow cytometry, confocal microscopy, and wide-field fluorescence microscopy, where consistency and reproducibility are essential.

Discover our complete, ready to use SCREEN-WELL® libraries for nephrotoxicity, cardiotoxicity, hepatotoxicity, and hematopoietic toxicity. Each contains compounds with defined and diverse organ-associated toxicity profiles. A variety of structurally and mechanistically different compound classes is included, as well as non-toxic controls. Compounds are dissolved in DMSO at 10mM and aliquoted into deepwell plates at 100 or 500μl per well for easy sample preparation. Our SCREEN-WELL® libraries are useful for predictive toxicology screening, including high-content protocols.

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Products for Kidney Injury and Nephrotoxicity

Enzo provides a variety of tools to detect markers of acute kidney injury, renal failure, and renal metabolism. These thoroughly validated, high-sensitivity kits are validated for a variety of species and samples types and are supported by antibodies and proteins to support biomarker detection and characterization.