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Compound Libraries

  • Cancer Library
  • Receptor De-orphaning
  • Chemical Genomics
  • Pathway Targeting
  • Lead Screening
  • Toxicity Libraries
  • Drug Repurposing


SCREEN-WELL® Compound Libraries complement our wide range of small molecules

Enzo Life Sciences has a long and successful track record in identifying, synthesizing and commercializing known bioactives for use as research tool compounds and in assembling relevant sets of focused compounds for screening.

Our long-standing, flagship SCREEN-WELL® Compound Library product family offers an easy, ready-to-use alternative for compound screening. Each library includes:

  • A unique collection of small molecules including inhibitors, activators and/or inducers.
  • Complete documentation set that highlights activity descriptions, plate positions, physical information and a structural database (SD) file
  • The ability to re-supply individual bulk compounds, custom libraries, or hard to source compounds


Advantages of Libraries

Extensive Offering

  • A unique offering of focused compound libraries comprised of FDA-approved compounds, natural products, compounds for receptor de-orphaning, chemical genomics, and pathway targeting.
  • Current catalog of over 2500 stand-alone small molecules including natural products, enzyme inhibitors, receptor ligands, drugs, lipids & fatty acids etc.

Proven and Consistent

  • Each SCREEN-WELL® Library collection incorporates years of scientific expertise resulting in libraries that contain the right compounds in the right combination.
  • Synthetic chemistry capability with a staff of organic chemists experienced in diverse synthetic methods and techniques.
  • Stringent quality control using state-of-the-art methods.


  • Libraries are composed of relevant small molecules, frequently including proprietary Enzo compounds


  • Individual compounds are also available for re-supply.
  • Ability to supply bulk quantities and custom compounds in the mg to kg scale.

Easy and Cost-efficient

  • All of our libraries come in a ready-to-screen format in biocompatible solvents, no reconstitution needed.
  • Ability to rapidly and inexpensively source compounds through a supplier network built over a 25 year history.

The SCREEN-WELL® Compound Libraries

SCREEN-WELL® Toxicity Libraries

SCREEN-WELL® libraries from Enzo Life Sciences for nephrotoxicity, cardiotoxicity, hepatotoxicity, and hematopoietic toxicity contain compounds with defined and diverse organ-associated toxicity profiles. A variety of structurally and mechanistically different compound classes are included, as well as nontoxic controls. Compounds are dissolved in DMSO at 10mM and aliquoted into deep-well plates at 100 or 500μl per well. The libraries are useful for predictive toxicology screening, including high-content protocols using cell based assays for early safety assessment.

  • Hundreds of compounds of defined and diverse toxicity
  • Nontoxic controls also included
  • Dissolved in DMSO and supplied in 96 well plates so they are ready to screen

Featured Literature

Predictive Toxicology

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