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SCREEN-WELL® Phosphatase Inhibitor library

BML-2834-0100 1 Library 100 µl/well 1,479.00 USD
BML-2834-0500 1 Library 500 µl/well 4,597.00 USD
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The SCREEN-WELL® Phosphatase Inhibitor Library contains 33 known phosphatase inhibitors of well-defined activity. Inhibitors are supplied dissolved in DMSO at 10 mM and aliquoted into deep-well plates at either 100 µl or 500 µl per well. The library is ideal for chemical genomics, assay development, and as a reference set for secondary screening. Includes inhibitors of these important phosphatases: Calcineurin(PP2B), JSP-1, PRL-1, CD45, PP1, PRL-3, CDC25, PP2A, PTEN, and many more.

Product Details

Use/Stability:Stable for at least one year from the date of receipt when stored at -80°C.
Shipping:Dry Ice
Long Term Storage:-80°C
Technical Info/Product Notes:
Regulatory Status:RUO - Research Use Only

Product Literature References

Phosphatase inhibitors BVT-948 and alexidine dihydrochloride inhibit sexual development of the malaria parasite Plasmodium berghei: X. Jia, et al.; Int. J. Parasitol. Drugs Drug Resist. 19, 81 (2022), Abstract; Full Text
Discovery of uncompetitive inhibitors of SapM that compromise intracellular survival of Mycobacterium tuberculosis: P.F. Soto, et al.; Sci. Rep. 11, 7667 (2021), Abstract; Full Text
Image-based high-throughput mapping of TGF-β-induced phosphocomplexes at a single-cell level: P. Lönn, et al.; Commun. Biol. 4, 1284 (2021), Abstract;
Eukaryotic phosphatase inhibitors enhance colistin efficacy in gram‐negative bacteria: W.T. Barker, et al.; Chem. Biol. Drug Des. 96, 1180 (2020), Abstract; Full Text
BML-265 and tyrphostin AG1478 disperse the Golgi apparatus and abolish protein transport in human cells: G. Boncompain, et al.; Front. Cell. Dev. Biol. 7, 232 (2019), Abstract; Full Text
Plasmodium berghei serine/threonine protein phosphatase PP5 plays a critical role in male gamete fertility: X. Zhu, et al.; Int. J. Parasitol. 49, 685 (2019), Abstract; Full Text
Therapeutic Chemical Screen Identifies Phosphatase Inhibitors to Reconstitute PKB Phosphorylation and Cardiac Contractility in ILK-Deficient Zebrafish: A. Pott, et al.; Biomolecules 8, 153 (2018), Abstract;
Identification of antipsychotic drug fluspirilene as a potential anti-glioma stem cell drug: Y. Dong, et al.; Oncotarget 8, 111728 (2017), Abstract; Full Text
Macrolides selectively inhibit mutant KCNJ5 potassium channels that cause aldosterone-producing adenoma: U.I. Scholl, et al.; J. Clin. Invest. 127, 2739 (2017), Abstract; Full Text
Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury: S. Martens, et al.; Cell Death Dis. 8, e2904 (2017), Abstract; Full Text
Therapeutic strategy for targeting aggressive malignant gliomas by disrupting their energy balance: A.M. Hegazy, et al.; J. Biol. Chem. 291, 21496 (2016), Abstract; Full Text
PRL-3 mediates the protein maturation of ULBP2 by regulating the tyrosine phosphorylation of HSP60: W.H. Leung, et al.; J. Immunol. 194, 2930 (2015), Abstract; Full Text
An inverse small molecule screen to design a chemically defined medium supporting long-term growth of Drosophila cell lines: M. Burnette, et al.; Mol. Biosyst. 10, 2713 (2014), Abstract; Full Text
High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines: A. Ketley, et al.; Hum. Mol. Genet. 23, 1551 (2014), Application(s): Screening of fibroblasts, Abstract; Full Text
High throughput screening for small molecule enhancers of the interferon signaling pathway to drive next-generation antiviral drug discovery: D.A. Patel, et al.; PLoS One 7, e36594 (2012), Abstract; Full Text
Small molecule screening identifies targetable zebrafish pigmentation pathways: S. Colanesi, et al.; Pigment Cell Melanoma Res. 25, 131 (2012), Abstract;
A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation: J. P. Saxe; Chem. Biol. 14, 1019 (2007), Abstract;

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