The SCREEN-WELL
® neurotransmitter library contains 661 CNS receptor ligands in a 96-well format. Ideal for screening or identifying recombinant orphan G protein-coupled receptors, target validation, secondary screening, validating new assays, and for routine pharmacological applications. Includes 13 classes of receptor ligands in 10 deep-well plates:
Adrenergics |
Histaminergics(Melatonin Ligands) |
Dopaminergics |
Ionotropic Glutamatergics |
Serotonergics |
Metabotropic Glutamatergics |
Opioids(Sigma ligands) |
GABAergics |
Cholinergics |
Purinergics (Adenosines) |
Each ligand is supplied in solution in a biocompatible solvent at a standard concentration of 10mM (Opioid peptides are supplied at a concentrations of 1mM). Plates are available as a complete set, or individually. Supporting data are included.
Product Details
Applications: | HTS
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Contents: | SCREEN-WELL® Adrenergic ligand library (BML-2811)
SCREEN-WELL® Dopaminergic ligand library (BML-2812)
SCREEN-WELL® Serotonergic ligand library (BML-2813)
SCREEN-WELL® Opioid ligand library (BML-2814)
SCREEN-WELL® Cholinergic ligand library (BML-2815)
SCREEN-WELL® Histaminergic ligand library (BML-2816)
SCREEN-WELL® Ionotropic Glutamatergic ligand library (BML-2817)
SCREEN-WELL® Metabotropic Glutamatergic ligand library (BML-2818)
SCREEN-WELL® GABAergic ligand library (BML-2819)
SCREEN-WELL® Purinergic ligand library (BML-2820) |
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Quantity: | 100µl/well or 500μl/well |
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Use/Stability: | Stable for at least one year from the date of receipt when stored at -80°C. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Shipped on Dry Ice |
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Long Term Storage: | -80°C |
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Technical Info/Product Notes: |  |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Screening inducers of neuronal BDNF gene transcription using primary cortical cell cultures from BDNF-luciferase transgenic mice: M. Fukuchi, et al.; Sci. Rep.
9, 11833 (2019),
Abstract;
Full Text
High-throughput screening for selective appetite modulators: A multibehavioral and translational drug discovery strategy: J. Jordi, et al.; Sci. Adv.
4, eaav1966 (2018),
Abstract;
Full Text
Identification of TAAR5 Agonist Activity of Alpha-NETA and Its Effect on Mismatch Negativity Amplitude in Awake Rats: A.A. Aleksandrov, et al.; Neurotox. Res.
34, 442 (2018),
Application(s): Screening for cAMP activity by bioluminescence resonance energy transfer in HEK293T cell culture,
Abstract;
Development and validation of a high-throughput calcium mobilization assay for the orphan receptor GPR88: A.M. Decker, et al.; J. Biomed. Sci.
24, 23 (2017),
Abstract;
Full Text
A KNIME-based analysis of the zebrafish photomotor response clusters the phenotypes of 14 classes of neuroactive molecules: D. Copmans, et al.; J. Biomol. Screen.
21, 427 (2016),
Abstract;
Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes: S.Y. Shaw et al.; Proc. Natl. Acad. Sci. USA
108, 492 (2011),
Abstract;
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