SCREEN-WELL^® Neurotransmitter library (10 plate set)



BML-2810-0100	1 Library	100 µl/well	11,237.00 USD

BML-2810-0500	1 Library	500 µl/well	34,695.00 USD
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The SCREEN-WELL^® neurotransmitter library contains 661 CNS receptor ligands in a 96-well format. Ideal for screening or identifying recombinant orphan G protein-coupled receptors, target validation, secondary screening, validating new assays, and for routine pharmacological applications. Includes 13 classes of receptor ligands in 10 deep-well plates:

Adrenergics	Histaminergics(Melatonin Ligands)
Dopaminergics	Ionotropic Glutamatergics
Serotonergics	Metabotropic Glutamatergics
Opioids(Sigma ligands)	GABAergics
Cholinergics	Purinergics (Adenosines)

Each ligand is supplied in solution in a biocompatible solvent at a standard concentration of 10mM (Opioid peptides are supplied at a concentrations of 1mM). Plates are available as a complete set, or individually. Supporting data are included.

Product Details

Applications:	HTS

Contents:	SCREEN-WELL® Adrenergic ligand library (BML-2811) SCREEN-WELL® Dopaminergic ligand library (BML-2812) SCREEN-WELL® Serotonergic ligand library (BML-2813) SCREEN-WELL® Opioid ligand library (BML-2814) SCREEN-WELL® Cholinergic ligand library (BML-2815) SCREEN-WELL® Histaminergic ligand library (BML-2816) SCREEN-WELL® Ionotropic Glutamatergic ligand library (BML-2817) SCREEN-WELL® Metabotropic Glutamatergic ligand library (BML-2818) SCREEN-WELL® GABAergic ligand library (BML-2819) SCREEN-WELL® Purinergic ligand library (BML-2820)

Quantity:	100µl/well or 500μl/well

Use/Stability:	Stable for at least one year from the date of receipt when stored at -80°C.

Handling:	Avoid freeze/thaw cycles.

Shipping:	Dry Ice

Long Term Storage:	-80°C

Technical Info/Product Notes:

Regulatory Status:	RUO - Research Use Only

Product Literature References

Screening inducers of neuronal BDNF gene transcription using primary cortical cell cultures from BDNF-luciferase transgenic mice: M. Fukuchi, et al.; Sci. Rep. 9, 11833 (2019), Abstract; Full Text

High-throughput screening for selective appetite modulators: A multibehavioral and translational drug discovery strategy: J. Jordi, et al.; Sci. Adv. 4, eaav1966 (2018), Abstract; Full Text

Identification of TAAR5 Agonist Activity of Alpha-NETA and Its Effect on Mismatch Negativity Amplitude in Awake Rats: A.A. Aleksandrov, et al.; Neurotox. Res. 34, 442 (2018), Application(s): Screening for cAMP activity by bioluminescence resonance energy transfer in HEK293T cell culture, Abstract;

Development and validation of a high-throughput calcium mobilization assay for the orphan receptor GPR88: A.M. Decker, et al.; J. Biomed. Sci. 24, 23 (2017), Abstract; Full Text

A KNIME-based analysis of the zebrafish photomotor response clusters the phenotypes of 14 classes of neuroactive molecules: D. Copmans, et al.; J. Biomol. Screen. 21, 427 (2016), Abstract;

Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes: S.Y. Shaw et al.; Proc. Natl. Acad. Sci. USA 108, 492 (2011), Abstract;

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