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Discover, Analyze, Quantify Cardiovascular Biomarkers

Tools For Discovery & Detection of Cardiac Disease Markers

The cardiovascular or circulatory system provides the body with essential nutrients and oxygen. Besides its nourishing function, it also plays a crucial role in inflammation and fighting infections, maintaining homeostasis, transporting hormones, and stabilizing body temperature. It also assists the body in recovering from damage and trauma. Although the system is extremely resilient, repeated or continuous stress can cause long-term damage and lead to cardiovascular diseases such as heart failure and stroke.

Cardiovascular disease is consistently ranked as the single largest cause of death in the world, and it may be caused by heart damage or vascular problems. Challenges in cardiovascular clinical development have caused researchers to take a closer look at cardiac function and metabolism. Enzo Life Sciences offers a comprehensive portfolio of products to enable discovery of cardiac risk factors as well as analysis of the cellular response to novel therapeutics for cardiovascular medicine.

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Discover, Analyze & Quantify Cardiovascular Biomarkers

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Protein Expression & Detection Tools

High Sensitivity, Low Background, True Results


Western Blot

  • Clear signals without the background
  • Sensitive results without expensive equipment
  • Reliably distinguish multiple targets
Western Blot


  • Detection of multiple antigens in a single tissue sample
  • Highest sensitivity, lower background
  • Broad palette of IHC stain colors to choose

Thousands of IHC and WB validated antibodies

Primary Antibody Search Tool


Our Worry-free Antibody Trial Program allows you to evaluate any of our antibodies of interest
for any new application or species not currently listed on our datasheet without risk.

Vascular Biology

Evaluate Vascular Growth, Inflammatory Responses And Coagulation

A complete portfolio of assays, enzymes and compounds to study vascular development, regulation and disease


Vascular Growth And Maintenance

ELISAs, Activity Assays and Abs for monitoring vascular changes such as clotting, fibrinolysis, and angiogenesis.

Vascular Growth And Maintenance

Inflammation And Disease

Accurate quantification for inflammatory compounds which play a role to vascular disease

  • PGE2 Immunoassays
  • Cytokine ELISAs
  • Markers for Vascular Disesase: FABP4, Haptoglobin, Adiponectin
Inflammation And Disease

Cardiac Function

A full range of antibodies, detection and activity assays for the reliable detection of cardiac disease biomarkers.


Monitor Calcium Mobilization

A Brighter, More Robust Fluorescent Assay for Calcium Mobilization
Intracellular calcium mobilization is critical to maintaining cellular depolarization during ventricular contraction. Enzo FluoForte dyes are optimized for high-throughput detection of intracellular calcium in living cells such as cardiomyocytes.

Monitor Calcium Mobilization

Screen For Inhibitors Of Phosphatase

Highly Cited Assay for Detection of Calcineurin Activity in Cardiac Myocytes
Calcineurin, a protein phosphatase involved in immune cell signaling, is a target for inhibitors such as everolimus which are used in heart transplantation to prevent rejection.

Screen For Inhibitors Of Phosphatase

Detect Markers of Myocardial Infarction

Highly specific, validated antibodies for natriuretic peptide detection
The brain natriuretic peptide (BNP) and atrial natriuretic peptide (ANP) are synthesized in cardiomyocytes in response to various forms of stress, and have a powerful vasodilatory effect. In clinical settings, normal levels of BNP and ANP can be used to rule out myocardial infarction.

Detect Markers of Myocardial Infarction

Evaluation of Cardiac Disease States

A full range of antibodies, detection and activity assays for the reliable detection of cardiac disease biomarkers.


Cardiac Injury

Most Sensitive ELISA for Detection of Troponin I
Troponin I is an inhibitory troponin subunit that acts in muscle relaxation and which, in its cardiac isoform, is a reliable marker of cardiac injury when identified in elevated levels in the bloodstream.

  • Most sensitive ELISA, detecting as little as 0.38 ng/ml of human troponin
  • Flexible sample types, including: cell lysates, plasma, and serum
  • Simple protocol with results in just 3.5 hours
  • Quantitative results as compared to Western blot analysis
Cardiac Injury

Prevention, Diagnosis & Monitoring

Accurately quantify cardiovascular biomarkers with Enzo’s high sensitivity ELISA kits and antibodies.

Prevention, Diagnosis & Monitoring

Vitamin D Deficiency

The Fastest High-Sensitivity Vitamin D ELISA kit
Low levels of vitamin D, an essential secosteroid, has been linked with an increased risk of heart disease and hypertension. Precise measurements of 25-hydroxyvitamin D in serum are critical to identify cardiac risk factors and to prevent vitamin D deficiency. The 25(OH)-Vitamin D assay is quick and accurate, making it the tool of choice for 25(OH)-Vitamin D detection.

Vitamin D Deficiency

Cardiovascular Drug Discovery

Innovative Tools for Profiling Cardiac Toxicity
Screen-Well® Cardiotoxicity Library
A focused collection of 131 compounds with defined and diverse cardiotoxicity. The library includes a variety of structurally and mechanistically different compound classes, as well as nontoxic controls. The compounds are dissolved in DMSO at 10mM and aliquoted into deep-well plates. The library is an essential tool for predictive toxicology screening and assay development.

Cardiovascular Drug Discovery

C-Reactive Protein

C-Reactive Protein (CRP) is a pentraxin family protein that is widely used as a biomarker for systemic inflammation and tissue injury. Its primary role in innate immunity is to function as an opsonin for pathogens via activation of the complement pathway and through binding to Fc gamma receptors. CRP has been shown to play an important role in a variety of pathological pathways.



  • Sensitive assay detects as little as 12.685 ng/ml in serum and plasma
  • Highly specific with negligible reactivity to other family members
  • Rapid results in just 1.5 hours

Typical standard curve shows broad range of detection



Measure Lp-PLA2 activity in vitro

The PLAQPRO® Lp-PLA2 Assay measures the enzyme activity of Lp-PLA2 (lipoprotein-associated phospholipase A2) in serum samples. Lp-PLA2 is produced by inflammatory cells and circulates primarily bound to LDL. The oxidization of LDL is an early key event in the pathogenesis of atherosclerosis. Increased levels of Lp-PLA2 have been found in atherosclerotic plaques and rupture lesions.

The PLAQPRO® Lp-PLA2 Assay is a colorimetric readout assay that measures the activity of Lp-PLA2 in serum samples.

  • Cost-efficient alternative to competitor’s Lp-PLA2 detection system
  • Designed to run on automated clinical chemistry analyzers
  • Includes ready-to-use calibration standards and QC controls
  • Wide analytical range from 0-400.0 nmol/min/mL

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Sensitive, Accurate Detection of Lp-PLA2 Activity

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