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Tools For Discovery & Detection of Cardiac Disease Markers

The cardiovascular or circulatory system provides the body with essential nutrients and oxygen. Besides its nourishing function, it also plays a crucial role in inflammation and fighting infections, maintaining homeostasis, transporting hormones, and stabilizing body temperature. It also assists the body in recovering from damage and trauma. Although the system is extremely resilient, repeated or continuous stress can cause long-term damage and lead to cardiovascular diseases such as heart failure and stroke.

Cardiovascular disease is consistently ranked as the single largest cause of death in the world, and it may be caused by heart damage or vascular problems. Challenges in cardiovascular clinical development have caused researchers to take a closer look at cardiac function and metabolism. Enzo Life Sciences offers a comprehensive portfolio of products to enable discovery of cardiac risk factors as well as analysis of the cellular response to novel therapeutics for cardiovascular medicine.

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Discover, Analyze & Quantify Cardiovascular Biomarkers
 

Pump Up Your Research

 

Signal Transduction
cAMP ELISAs
cGMP ELISAs

Blood Clotting & Fibrinolysis
Fibrinogen ELISA Kit
Plasminogen ELISA Kit
Abs (Fibrinogen, D-dimer)

Vasorelaxation & Vasoconstriction
Endothelin ELISA Kit, proteins, Abs
Leukotoxin A, Leukotoxin B
Angiotensin ELISAs

RELATED PRODUCTS
Immunohistochemistry

POLYVIEW® PLUS HRP Detection Kits
MULTIVIEW® Multiplex Detection Kits
HIGHDEF® Chromogens
Validated Antibodies

Protein Expression & Detection Tools

High Sensitivity, Low Background, True Results

 

Western Blot





  • Clear signals without the background
  • Sensitive results without expensive equipment
  • Reliably distinguish multiple targets
Western Blot

Immunohistohemistry





  • Detection of multiple antigens in a single tissue sample
  • Highest sensitivity, lower background
  • Broad palette of IHC stain colors to choose
Immunohistochemistry
 

Thousands of IHC and WB validated antibodies

Primary Antibody Search Tool



 

Our Worry-free Antibody Trial Program allows you to evaluate any of our antibodies of interest
for any new application or species not currently listed on our datasheet without risk.

Vascular Biology

Evaluate Vascular Growth, Inflammatory Responses And Coagulation

A complete portfolio of assays, enzymes and compounds to study vascular development, regulation and disease

 

Vascular Growth And Maintenance

ELISAs, Activity Assays and Abs for monitoring vascular changes such as clotting, fibrinolysis, and angiogenesis.

Vascular Growth And Maintenance

Inflammation And Disease

Accurate quantification for inflammatory compounds which play a role to vascular disease

  • PGE2 Immunoassays
  • Cytokine ELISAs
  • Markers for Vascular Disesase: Adiponectin, Autophagy, VEGF
Inflammation And Disease
 

Monitor Signal Transduction in Cardiac Muscle

High-Purity Antibodies & Flexible Activity Assays for Complete Analysis of Cardiac Activity

 

Monitor Calcium Mobilization

A Brighter, More Robust Fluorescent Assay for Calcium Mobilization

Intracellular calcium mobilization is critical to maintaining cellular depolarization during ventricular contraction. Enzo FluoForte dyes are optimized for high-throughput detection of intracellular calcium in living cells such as cardiomyocytes.

Monitor Calcium Mobilization

Screen For Inhibitors Of Phosphatase

Highly Cited Assay for Detection of Calcineurin Activity in Cardiac Myocytes

Calcineurin, a protein phosphatase involved in immune cell signaling, is a target for inhibitors such as everolimus which are used in heart transplantation to prevent rejection.

Screen For Inhibitors Of Phosphatase

Renin-Angiotensin-Aldosterone System

Highly Sensitive ELISA Kits and Validated Antibodies

The renin-angiotensin–aldosterone system (RAAS) is a critical regulator of blood volume and systemic vascular resistance. It is composed of three major compounds: renin, angiotensin II, and aldosterone.

Detect Markers of Myocardial Infarction

Quantify Cardiovascular Biomarkers

A full range of antibodies, detection and activity assays for the reliable detection of cardiac disease biomarkers.

 

Risk Factors of Cardiovascular

Quantitate Lp-PLA2 Activity In Vitro

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a calcium-independent lipase primarily produced by monocytes and macrophages, and it is recognized as an independent risk factor for cardiovascular disease (CVD).

  • Wide analytical measurement range from 0 – 400.0 nmol/min/mL
  • Analytical sensitivity of 0.236 nmol/min/mL
  • Designed to run on automated clinical chemistry analyzers
  • Ready-to-use calibration standards and QC controls are provided
PLAQPRO™ Lp-PLA2 Assay

Prevention, Diagnosis & Monitoring

Accurately quantify cardiovascular biomarkers with Enzo’s high sensitivity ELISA kits and antibodies.

Prevention, Diagnosis & Monitoring
 

Vitamin D Deficiency

The Fastest High-Sensitivity Vitamin D ELISA kit

Low levels of vitamin D, an essential secosteroid, has been linked with an increased risk of heart disease and hypertension. Precise measurements of 25-hydroxyvitamin D in serum are critical to identify cardiac risk factors and to prevent vitamin D deficiency. The 25(OH)-Vitamin D assay is quick and accurate, making it the tool of choice for 25(OH)-Vitamin D detection.

Vitamin D Deficiency

Cardiovascular Drug Discovery

Innovative Tools for Profiling Cardiac Toxicity
Screen-Well® Cardiotoxicity Library

A focused collection of 131 compounds with defined and diverse cardiotoxicity. The library includes a variety of structurally and mechanistically different compound classes, as well as nontoxic controls. The compounds are dissolved in DMSO at 10mM and aliquoted into deep-well plates. The library is an essential tool for predictive toxicology screening and assay development.

Cardiovascular Drug Discovery
 

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