Tools For Discovery & Detection of Cardiac Disease Markers
The cardiovascular or circulatory system provides the body with essential nutrients and oxygen. Besides its nourishing function, it also plays a crucial role in inflammation and fighting infections, maintaining homeostasis, transporting hormones, and stabilizing body temperature. It also assists the body in recovering from damage and trauma. Although the system is extremely resilient, repeated or continuous stress can cause long-term damage and lead to cardiovascular diseases such as heart failure and stroke.
Cardiovascular disease is consistently ranked as the single largest cause of death in the world, and it may be caused by heart damage or vascular problems. Challenges in cardiovascular clinical development have caused researchers to take a closer look at cardiac function and metabolism. Enzo Life Sciences offers a comprehensive portfolio of products to enable discovery of cardiac risk factors as well as analysis of the cellular response to novel therapeutics for cardiovascular medicine.
Our Worry-free Antibody Trial Program allows you to evaluate any of our antibodies of interest for any new application or species not currently listed on our datasheet without risk.
Vascular Biology
Evaluate Vascular Growth, Inflammatory Responses And Coagulation
A complete portfolio of assays, enzymes and compounds to study vascular development, regulation and disease
Vascular Growth And Maintenance
ELISAs, Activity Assays and Abs for monitoring vascular changes such as clotting, fibrinolysis, and angiogenesis.
Inflammation And Disease
Accurate quantification for inflammatory compounds which play a role to vascular disease
PGE2 Immunoassays
Cytokine ELISAs
Markers for Vascular Disesase: Adiponectin, Autophagy, VEGF
Monitor Signal Transduction in Cardiac Muscle
High-Purity Antibodies & Flexible Activity Assays for Complete Analysis of Cardiac Activity
Monitor Calcium Mobilization
A Brighter, More Robust Fluorescent Assay for Calcium Mobilization
Intracellular calcium mobilization is critical to maintaining cellular depolarization during ventricular contraction. Enzo FluoForte dyes are optimized for high-throughput detection of intracellular calcium in living cells such as cardiomyocytes.
Screen For Inhibitors Of Phosphatase
Highly Cited Assay for Detection of Calcineurin Activity in Cardiac Myocytes
Calcineurin, a protein phosphatase involved in immune cell signaling, is a target for inhibitors such as everolimus which are used in heart transplantation to prevent rejection.
Renin-Angiotensin-Aldosterone System
Highly Sensitive ELISA Kits and Validated Antibodies
The renin-angiotensin–aldosterone system (RAAS) is a critical regulator of blood volume
and systemic vascular resistance. It is composed of three major compounds: renin,
angiotensin II, and aldosterone.
Quantify Cardiovascular Biomarkers
A full range of antibodies, detection and activity assays for the reliable detection of cardiac disease biomarkers.
Risk Factors of Cardiovascular
Quantitate Lp-PLA2 Activity In Vitro
Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a calcium-independent lipase primarily produced by monocytes and macrophages, and it is recognized as an independent risk factor for cardiovascular disease (CVD).
Wide analytical measurement range from 0 – 400.0 nmol/min/mL
Analytical sensitivity of 0.236 nmol/min/mL
Designed to run on automated clinical chemistry analyzers
Ready-to-use calibration standards and QC controls are provided
Prevention, Diagnosis & Monitoring
Accurately quantify cardiovascular biomarkers with Enzo’s high sensitivity ELISA kits and antibodies.
Vitamin D Deficiency
The Fastest High-Sensitivity Vitamin D ELISA kit
Low levels of vitamin D, an essential secosteroid, has been linked with an increased risk of heart disease and hypertension. Precise measurements of 25-hydroxyvitamin D in serum are critical to identify cardiac risk factors and to prevent vitamin D deficiency.
The 25(OH)-Vitamin D assay is quick and accurate, making it the tool of choice for 25(OH)-Vitamin D detection.
Cardiovascular Drug Discovery
Innovative Tools for Profiling Cardiac Toxicity
Screen-Well® Cardiotoxicity Library
A focused collection of 131 compounds with defined and diverse cardiotoxicity. The library includes a variety of structurally and mechanistically different compound classes, as well as nontoxic controls. The compounds are dissolved in DMSO at 10mM and aliquoted into deep-well plates. The library is an essential tool for predictive toxicology screening and assay development.