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United States 

IL-11 (human), (recombinant)

ENZ-PRT242-0010 10 µg 342.00 USD
ENZ-PRT242-0100 100 µg 1,962.00 USD
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Product Details

Alternative Name:Interleukin-11, AGIF, Adipogenesis Inhibitory Factor, Oprelvekin
MW:~19.3 kDa
Source:Produced in E. coli. Contains 179 amino acids.
UniProt ID:P20809
Formulation:Lyophilized from a sterile (0.2 micron) filtered solution containing 0.1% Trifluoroacetic Acid (TFA).
Purity:≥95% (SDS-PAGE)
Endotoxin Content:≤1 EU/µg protein (LAL test)
Biological Activity:TF-1 cell proliferation; ≤ 10 ng/mL (≥ 1.0 x 105 units/mg).
Reconstitution:Reconstitute in sterile water at 0.1 mg/mL.
Shipping:Ambient Temperature
Long Term Storage:-80°C
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
Scientific Background:Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover.
Regulatory Status:RUO - Research Use Only

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