Sensitive measurement of CRP, detecting as little as 8.876 ng/ml
Negligible reactivity for similar family members
High throughput format with results in 3 hours for up to 40 samples in duplicate
Fully quantitative results that surpass semi-quantitative Western blot analysis
The CRP (human) ELISA kit is a complete, colorimetric, competitive immunoassay kit for the quantitative determination of human CRP in serum and plasma with results in 3 hours.
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Product Details
Alternative Name:
C-reactive protein
Sensitivity:
8.876 ng/ml (range 10 - 810 ng/ml)
Assay Time:
3 hours
Applications:
ELISA, Colorimetric detection
Application Notes:
For the quantitative determination of human C-reactive protein in serum and plasma.
Wavelength:
450 nm
Species reactivity:
Human
Crossreactivity:
No cross reactivity to similar family molecule (<0.015% human serum amyloid P component).
Use/Stability:
All components of this kit are stable at 4°C until the kit's expiration date except for the CRP Standard, CRP Antibody, and CRP Conjugate which must be stored at -20°C.
C-Reactive Protein (CRP) is a pentraxin family protein that is widely used as a biomarker for systemic inflammation and tissue injury. Its primary role in innate immunity is to function as an opsonin for pathogens via activation of the complement pathway and through binding to Fc gamma receptors. CRP has been shown to play an important role in a variety of pathological pathways such as chronic inflammatory disorders, myocardial infarction, pulmonary disorders, atherosclerosis, cancer, metabolic syndrome, and depression.
Lower Life Satisfaction and Inflammation in African American Adults: Body Adiposity Mediation and Sex Moderation: K.A.S. Wickrama, et al.; J. Pers. Med. 12, 745 (2022), Abstract;
Methylation of genes and regulation of inflammatory processes on emotional response in young adults with alcoholic parents: J.L. Scholl, et al.; Brain Behav. Immun. Health 25, 100505 (2022), Abstract;
Melatonin supplementation improves oxidative and inflammatory state in the blood of professional athletes during the preparatory period for competitions: J. Czuczejko, et al.; Free Radic. Res. 53, 198 (2019), Application(s): Human serum, Abstract;
Characterisation of gut, lung, and upper airways microbiota in patients with non-small cell lung carcinoma: Study protocol for case-control observational trial: R. Bingula, et al.; Medicine (Baltimore) 97, e13676 (2018), Abstract; Full Text
Age dependent levels of plasma homocysteine and cognitive performance: A. Agrawal, et al.; Behav. Brain Res. 283C, 139 (2015), Application(s): ELISA using human plasma, Abstract;
Produced in E. coli. Human IL-1β (interleukin-1β) (aa 117-270) is fused to a linker peptide (10 aa) and an N-terminal FLAG®-tag., ≥90% (SDS-PAGE) | Print as PDF
Produced in E. coli. The extracellular domain of human TNF-α (tumor necrosis factor-α) (aa 85-223) is fused at the N-terminus to a linker peptide (8 aa) and a FLAG®-tag., ≥95% (SDS-PAGE), ELISA | Print as PDF
