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SCREEN-WELL® Hepatotoxicity library

Essential standards for predictive toxicology screening
BML-2851-0500 1 Library 500 µl/well Inquire for pricing
BML-2851-0100 1 Library 100 µl/well Inquire for pricing
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The SCREEN-WELL® Hepatotoxicity Library is a focused collection of 238 compounds with defined and diverse hepatotoxicity, including steatosis, mitochondrial toxicity, Mallory body formation, cholestatic effects, and many more. A variety of structurally and mechanistically different compound classes are included, as well as nontoxic controls. The compounds are dissolved in DMSO at 10mM and aliquoted into deep-well plates. The library is an essential tool for predictive toxicology screening and assay development.

Product Specification

Contents:238 compounds with defined and diverse hepatotoxicity. A variety of structurally and mechanistically different compound classes, as well as nontoxic controls, are included.
Quantity:100 µl/well or 500 µl/well
Concentration:DMSO solutions (10mM).
Use/Stability:Stable for at least one year from the date of receipt when stored at -80°C.
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Dry Ice
Long Term Storage:-80°C
Technical Info/Product Notes:

Application Note (Predictive Toxicology Application):
Predictive High-Content/High-Throughput Assays for Hepatotoxicity Using Induced Pluripotent Stem Cell (iPSC)-Derived Hepatocytes.
Three Dimensional Hepatotoxicity Screening using Corning® HepatoCells, the Spheroid Microplate, and the SCREEN-WELL® Hepatotoxicity Library.

Product Literature References

High-Content Assays for Hepatotoxicity Using Induced Pluripotent Stem Cell-Derived Cells: O. Sirenko, et al.; Assay Drug Dev. Technol. 12, 43 (2014), Abstract; Full Text

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