The SCREEN-WELL® Cancer Library is a collection of 275 compounds that can be used for cancer inhibitor screening and assay development. The library contains small molecules affecting mTOR, aurora kinases, tyrosine kinases, PI3K, and HDAC, as well as many structurally and mechanistically different compound classes. This library is an essential tool for cancer inhibitor screening and drug development. The compounds are dissolved in DMSO at 10 mM and aliquoted into 96-well deep-well plates at 100 µL per well.
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Product Details
Applications:
HTS
Contents:
275 structurally and mechanistically different compounds, as well as nontoxic controls.
Quantity:
100 µl/well
Concentration:
DMSO solutions (10mM).
Use/Stability:
Stable for at least one year from the date of receipt when stored at -80°C.
Handling:
Avoid freeze/thaw cycles.
Shipping:
Dry Ice
Long Term Storage:
-80°C
Technical Info/Product Notes:
Regulatory Status:
RUO - Research Use Only
Product Literature References
A novel strategy for combination of clofarabine and pictilisib is synergistic in gastric cancer: S. Khalafi, et al.; Transl. Oncol. 15, 101260 (2022), Abstract;
Multiplex assay that distinguishes between healthy, early apoptotic, late apoptotic and necrotic cells, compatible with GFP and other fluorescent probes (blue or cyan)
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