The SCREEN-WELL® Ion Channel Ligand Library contains 70 ion channel blockers and openers for use in characterizing and identifying ion channels in individual cells or tissue.
Product Details
| Applications: | HTS
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| Concentration: | 10mM in DMSO. |
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| Use/Stability: | Stable for at least one year from the date of receipt when stored at -80°C. |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Technical Info/Product Notes: |  |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Cardiac Rhythm and Molecular Docking Studies of Ion Channel Ligands with Cardiotoxicity in Zebrafish: B.P. Sampurna, et al.; Cells
8, 566 (2019),
Abstract;
Full Text
Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation: M. Segovia, et al.; Cancer Cell
35, 767 (2019),
Abstract;
Full Text
Macrolides selectively inhibit mutant KCNJ5 potassium channels that cause aldosterone-producing adenoma: U.I. Scholl, et al.; J. Clin. Invest.
127, 2739 (2017),
Abstract;
Full Text
Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy: Y. Chen, et al.; Sci. Rep.
7, 45366 (2017),
Abstract;
A KNIME-based analysis of the zebrafish photomotor response clusters the phenotypes of 14 classes of neuroactive molecules: D. Copmans, et al.; J. Biomol. Screen.
21, 427 (2016),
Abstract;
An inverse small molecule screen to design a chemically defined medium supporting long-term growth of Drosophila cell lines: M. Burnette, et al.; Mol. Biosyst.
10, 2713 (2014),
Abstract;
Full Text
Development and implementation of a high-throughput compound screening assay for targeting disrupted ER calcium homeostasis in Alzheimer's disease: K. Honarnejad, et al.; PLoS One
8, e80645 (2013),
Abstract;
Full Text
Cardiac glycosides are potent inhibitors of interferon-β gene expression: J. Ye, et al.; Nat. Chem. Biol.
7, 25 (2011),
Abstract;
Full Text
A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators: P. Stoilov, et al.; PNAS
105, 11218 (2008),
Abstract;
