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SCREEN-WELL® Ion Channel ligand library

BML-2805-0100 1 Library 100 µl/well 1,080.00 USD
BML-2805-0500 1 Library 500 µl/well 3,244.00 USD
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The SCREEN-WELL® Ion Channel Ligand Library contains 70 ion channel blockers and openers for use in characterizing and identifying ion channels in individual cells or tissue.

Product Details

Concentration:10mM in DMSO.
Use/Stability:Stable for at least one year from the date of receipt when stored at -80°C.
Shipping:Dry Ice
Long Term Storage:-80°C
Technical Info/Product Notes:
Regulatory Status:RUO - Research Use Only

Product Literature References

Cardiac Rhythm and Molecular Docking Studies of Ion Channel Ligands with Cardiotoxicity in Zebrafish: B.P. Sampurna, et al.; Cells 8, 566 (2019), Abstract; Full Text
Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation: M. Segovia, et al.; Cancer Cell 35, 767 (2019), Abstract; Full Text
Macrolides selectively inhibit mutant KCNJ5 potassium channels that cause aldosterone-producing adenoma: U.I. Scholl, et al.; J. Clin. Invest. 127, 2739 (2017), Abstract; Full Text
Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy: Y. Chen, et al.; Sci. Rep. 7, 45366 (2017), Abstract;
A KNIME-based analysis of the zebrafish photomotor response clusters the phenotypes of 14 classes of neuroactive molecules: D. Copmans, et al.; J. Biomol. Screen. 21, 427 (2016), Abstract;
An inverse small molecule screen to design a chemically defined medium supporting long-term growth of Drosophila cell lines: M. Burnette, et al.; Mol. Biosyst. 10, 2713 (2014), Abstract; Full Text
Development and implementation of a high-throughput compound screening assay for targeting disrupted ER calcium homeostasis in Alzheimer's disease: K. Honarnejad, et al.; PLoS One 8, e80645 (2013), Abstract; Full Text
Cardiac glycosides are potent inhibitors of interferon-β gene expression: J. Ye, et al.; Nat. Chem. Biol. 7, 25 (2011), Abstract; Full Text
A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators: P. Stoilov, et al.; PNAS 105, 11218 (2008), Abstract;

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Ion channel Compound library
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