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SCREEN-WELL® Nuclear Receptor ligand library

BML-2802-0500 1 Library 500 µl/well Inquire for pricing
BML-2802-0100 1 Library 100 µl/well Inquire for pricing
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The SCREEN-WELL® Nuclear Receptor Ligand Library contains 74 compounds with defined, putative and potential activity at nuclear receptors. Receptor agonists and antagonists are included. The library consists of a chemically diverse group of compounds which are supplied dissolved in DMSO at 10 mM (1mM for 5 compounds) and aliquoted into deep-well, 96-well plates at 500 µl or 100 µl per well. The library is an ideal tool for chemical genomics, receptor de-orphaning and other routine pharmacological applications. The library includes ligands for the following classes of nuclear receptors: AHR, CAR, ER, FXR, LXR, PPAR, PXR, RAR, RXR, VDR, and other steroid receptors.

Product Details

Use/Stability:Stable for at least one year from the date of receipt when stored at -80°C.
Shipping:Shipped on Dry Ice
Long Term Storage:-80°C
Technical Info/Product Notes:

Application Note: High Throughput Screening Applications.
Regulatory Status:RUO - Research Use Only

Product Literature References

Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency: Y. Yang, et al.; Cell 169, 243 (2017), Abstract;
Use of differential scanning fluorimetry to identify nuclear receptor ligands: K.A. DeSantis, et al.; Methods Mol. Biol. 1443, 21 (2016), Abstract;

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