The SCREEN-WELL® Nuclear Receptor Ligand Library contains 74 compounds with defined, putative and potential activity at nuclear receptors. Receptor agonists and antagonists are included. The library consists of a chemically diverse group of compounds which are supplied dissolved in DMSO at 10 mM (1mM for 5 compounds) and aliquoted into deep-well, 96-well plates at 500 µl or 100 µl per well. The library is an ideal tool for chemical genomics, receptor de-orphaning and other routine pharmacological applications. The library includes ligands for the following classes of nuclear receptors: AHR, CAR, ER, FXR, LXR, PPAR, PXR, RAR, RXR, VDR, and other steroid receptors.
Product Details
| Applications: | HTS
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| Use/Stability: | Stable for at least one year from the date of receipt when stored at -80°C. |
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| Shipping: | Shipped on Dry Ice |
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| Long Term Storage: | -80°C |
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| Technical Info/Product Notes: | 
Application Note: High Throughput Screening Applications. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency: Y. Yang, et al.; Cell
169, 243 (2017),
Abstract;
Use of differential scanning fluorimetry to identify nuclear receptor ligands: K.A. DeSantis, et al.; Methods Mol. Biol.
1443, 21 (2016),
Abstract;
