The SCREEN-WELL® Endocannabinoid Library contains 58 compounds with defined, putative, potential or speculative activity at cannabinoid (CB) and vanilloid (VR) receptors. The library is an array of 10 different fatty acids and 6 different polar head groups. Ligands are supplied dissolved in biocompatible solvents at 1 mM and aliquoted into deep-well plates at 100 µl per well. The library is a rich source of ligands for receptor de-orphaning. Includes the following classes of ligands: Amides, Ethanolamides, Lipo-amino acids, Acyl-GABAs, Acyl-dopamines.
Product Details
| Applications: | HTS
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| Use/Stability: | Stable for at least one year from the date of receipt when stored at -80°C. |
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| Shipping: | Shipped on Dry Ice |
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| Long Term Storage: | -80°C |
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| Technical Info/Product Notes: |  |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
A Glucuronic Acid-Palmitoylethanolamide Conjugate (GLUPEA) Is an Innovative Drug Delivery System and a Potential Bioregulator: E. Manzo, et al.; Cells
10, 450 (2021),
Abstract;
Full Text
Modulation of pantothenate kinase 3 activity by small molecules that interact with the substrate/allosteric regulatory domain: R. Leonardi, et al.; Chem. Biol.
17, 892 (2010),
Abstract;
Full Text
Lipid G protein-coupled receptor ligand identification using β-arrestin PathHunter™ assay: H. Yin, et al.; J. Biol. Chem.
284, 12328 (2009),
Abstract;
Full Text
A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators: P. Stoilov, et al.; PNAS
105, 11218 (2008),
Abstract;
General Literature References
Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay: H. Yin, et al.; J. Biol. Chem.
284, 12328 (2009),
Abstract;
