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Glutathione peroxidase activity kit

ADI-900-158 5x96 wells 771.00 USD
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  • Validated in a variety of sample types
  • Fast, accurate assay results in less than 30 minutes
  • Convenient 96 well plate format for higher throughput.
The Glutathione Peroxidase activity kit is a convenient 96-well plate based assay for the higher throughput analysis of glutathione peroxidase activity in a variety of sample matrices in just 30 minutes.

Product Details

Alternative Name:GPx
Applications:Colorimetric detection
Activity assay
Application Notes:For the measurement of glutathione peroxidase in cell lysates, plasma, and tissue from any species.
Shipping:Blue Ice
Long Term Storage:-20°C
Contents:Microtiter plate, Assay buffer concentrate, Reaction mix, Glutathione reductase, GSSG
Scientific Background:Glutathione, a major intracellular non-protein thiol, protects against free radical damage by providing reducing equivalents for several key antioxidant enzymes. In addition, glutathione acts as a scavenger of hydroxyl radicals and nascent oxygen. Elevated glutathione levels are associated with a reduced rate of illness, higher levels of self-rated health, lower cholesterol, lower body mass index, and lower blood pressure among the elderly. Glutathione provides a primary defense system for the removal of oxidants in the brain. Studies have revealed a correlation between low glutathione levels and damage to neurons that manufacture dopamine, suggesting a link to Parkinson's disease.
Regulatory Status:RUO - Research Use Only

Product Literature References

Antioxidant, Anti-Apoptotic, and Anti-Inflammatory Effects of Farrerol in a Mouse Model of Obstructive Uropathy: J.Y. Kim, et al.; Curr. Issues Mol. Biol. 45, 337 (2023), Abstract;
Antioxidant, Antiapoptotic, and Anti-Inflammatory Effects of Hesperetin in a Mouse Model of Lipopolysaccharide-Induced Acute Kidney Injury: A.Y. Yang, et al.; Molecules 28, 2759 (2023), Abstract;
Evaluation of the Antioxidant Activity of Levetiracetam in a Temporal Lobe Epilepsy Model: I.I. Mejía, et al.; Biomedicines 11, 848 (2023), Abstract;
c-Abl tyrosine kinase inhibition attenuate oxidative stress-induced pancreatic β-Cell dysfunction via glutathione antioxidant system: U. Karunakaran, et al.; Transl. Res. 249, 74 (2022), Abstract;
Esophageal Cancer Stem-like Cells Resist Ferroptosis-Induced Cell Death by Active Hsp27-GPX4 Pathway: C.C. Liu, et al.; Biomolecules 12, 48 (2022), Abstract;
Ferredoxin:NADP(H) Oxidoreductase Abundance and Location Influences Redox Poise and Stress Tolerance: M. Kozuleva, et al.; Plant Physiol. 172, 1480 (2022), Abstract;
Hispidulin Ameliorates Endotoxin-Induced Acute Kidney Injury in Mice: K. Kim, et al.; Molecules 27, 2019 (2022), Abstract;
Agglomeration State of Titanium-Dioxide (TiO 2) Nanomaterials Influences the Dose Deposition and Cytotoxic Responses in Human Bronchial Epithelial Cells at the Air-Liquid Interface: S. Murugadoss, et al.; Nanomaterials 11, 3226 (2021), Abstract;
Engineered Sumoylation-Deficient Prdx6 Mutant Protein-Loaded Nanoparticles Provide Increased Cellular Defense and Prevent Lens Opacity: B. Chhunchha, et al.; Antioxidants 10, 1245 (2021), Abstract;
Oxidative Stress Markers and Antioxidant Enzymes in Children and Adolescents with Depressive Disorder and Impact of Omega-3 Fatty Acids in Randomised Clinical Trial: B. Katrenčíková, et al.; Antioxidants 10, 1256 (2021), Abstract;
Anti-Diabetic Effect of Cotreatment with Quercetin and Resveratrol in Streptozotocin-Induced Diabetic Rats: D.K. Yang & H.S. Kang; Biomol. Ther. (Seoul) 26, 130 (2018), Application(s): Rat serum, Abstract; Full Text
Sumoylation-deficient Prdx6 gains protective function by amplifying enzymatic activity and stability and escapes oxidative stress-induced aberrant Sumoylation: B. Chhunchha, et al.; Cell Death Dis. 8, e2525 (2017), Abstract; Full Text
Mitochondrial peroxiredoxin-3 protects against hyperglycemia induced myocardial damage in Diabetic cardiomyopathy: S. Arkat, et al.; Free Radic. Biol. Med. 97, 489 (2016), Abstract;
Reformulated meat products protect against ischemia-induced cardiac damage: M.C. Asensio-Lopez, et al.; Food Funct. 7, 992 (2016), Abstract;
S‐Glutathionylation of Keap1: a new role for glutathione S‐transferase pi in neuronal protection: A.N. Carvalho, et al.; FEBS Lett. 590, 1455 (2016), Abstract;
Antidiabetic Effects of Yam (Dioscorea batatas) and Its Active Constituent, Allantoin, in a Rat Model of Streptozotocin-Induced Diabetes: H.-K. Go, et al.; Nutrients 7, 8532 (2015), Application(s): Rat serum, Abstract; Full Text
Differences in Redox Regulatory Systems in Human Lung and Liver Tumors Suggest Different Avenues for Therapy: R. Tobe, et al.; Cancers (Basel) 7, 2262 (2015), Application(s): GPX activities measured in protein extracts , Abstract; Full Text
ErbB2 overexpression upregulates antioxidant enzymes, reduces basal levels of reactive oxygen species, and protects against doxorubicin cardiotoxicity: F. Belmonte, et al.; Am. J. Physiol. Heart Circ. Physiol. 309, H1271 (2015), Abstract; Full Text
Defensive mechanism in cholangiocarcinoma cells against oxidative stress induced by chlorine e6-based photodynamic therapy: H.M. Lee, et al.; Drug Des. Devel. Ther. 8, 1451 (2014), Abstract; Full Text
Ets-1 global gene expression profile reveals associations with metabolism and oxidative stress in ovarian and breast cancers: M.L. Verschoor, et al.; Cancer Metab. 1, 17 (2013), Abstract; Full Text
Involvement of ferritin heavy chain in preventive effect of metformin against doxorubicin-induced cardiotoxicity: M.C. Asensio-Lopez, et al.; Free Radic. Biol. Med. 57, 188 (2013), Abstract;
Gene Expression and Physiological Changes of Different Populations of the Long-Lived Bivalve Arctica islandica under Low Oxygen Conditions: E.E. Philipp, et al.; PLoS One 7, e44621 (2012), Abstract; Full Text

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