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Proteases

Rapidly screen inhibitors of key enzymes regulating elasticity







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Protease Assay Kits & Substrates

Neutrophil elastase colorimetric drug discovery kit

Neutrophil elastase is a serine protease found in polymorphonuclear neutrophils that functions in inflammation.

  • Rapid, sensitive, and reliable results for neutrophil elastase activity or the effects of inhibitors
  • Kit includes elastatinal, a known elastase inhibitor, as a control
  • Amenable to high throughput screening


Percent Inhibition of HNE by Elastatinal


Using the elastase inhibitor, elastatinal, the % activity remaining can be calculated

 

Cathepsin D & E substrate (fluorogenic) 

Synthetic, ≥95% (HPLC) | Print as PDF
 
BML-P145-0001 1 mg 164.00 USD
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Cathepsin K drug discovery kit 

Fluorescent detection, HTS, Activity assay | Print as PDF
 
BML-AK430-0001 96 wells 505.00 USD
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Cathepsin S drug discovery kit 

Fluorescent detection, HTS, Activity assay | Print as PDF
 
BML-AK431-0001 96 wells 505.00 USD
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CV-Cathepsin B detection kit 

Fluorescence microscopy, Fluorescent detection | Print as PDF
 
BML-AK125-0001 1 Kit 259.00 USD
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CV-Cathepsin K detection kit 

Fluorescence microscopy, Fluorescent detection | Print as PDF
 
BML-AK126-0001 1 Kit 284.00 USD
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CV-Cathepsin L detection kit 

Fluorescence microscopy, Fluorescent detection | Print as PDF
 
BML-AK127-0001 1 Kit 344.00 USD
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Granzyme B assay kit for drug discovery 

Colorimetric detection, Fluorescent detection, HTS, Activity assay | Print as PDF
 
BML-AK711-0001 96 wells 565.00 USD
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Neutrophil elastase colorimetric drug discovery kit 

Colorimetric detection, HTS, Activity assay | Print as PDF
 
BML-AK497-0001 96 wells 469.00 USD
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OMNICATHEPSIN® fluorogenic substrate 

65147-22-0, ≥99% | Print as PDF
 
BML-P139-0010 10 mg 65.00 USD
 
BML-P139-0050 50 mg 232.00 USD
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PMN-Elastase (human) ELISA kit 

ELISA | Print as PDF
 
ALX-850-265-KI01 96 wells 703.00 USD
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Protease Specific Antibodies

Every Enzo antibody is backed by our Worry-free Antibody Trial Program.

 

Cathepsin B (human) polyclonal antibody 

ELISA, WB | Print as PDF
 
BML-SA361-0100 100 µl 204.00 USD
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Cathepsin D (human) polyclonal antibody 

WB | Print as PDF
 
BML-SA398-0100 100 µl 190.00 USD
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Cathepsin G (human) polyclonal antibody 

ELISA, WB | Print as PDF
 
BML-SA354-0100 100 µl 180.00 USD
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Cathepsin H (human) polyclonal antibody 

ELISA, WB | Print as PDF
 
BML-SA355-0100 100 µl 180.00 USD
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Cathepsin L (human) polyclonal antibody 

ELISA, WB | Print as PDF
 
BML-SA362-0100 100 µl 204.00 USD
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Cathepsin L/procathepsin L (human) monoclonal antibody (CLP 1/36) 

IHC (PS), WB | Print as PDF
 
ALX-804-292-C200 200 µg 419.00 USD
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Cathepsin L/procathepsin L monoclonal antibody (CPLH 3G10) 

ELISA, WB | Print as PDF
 
ALX-804-293-C200 200 µg 590.00 USD
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Collagen type I monoclonal antibody (5D8) 

ELISA, IHC, WB | Print as PDF
 
BPD-CSI-008-01-1 1 mg Inquire for pricing
 
BPD-CSI-008-01-02 200 µg Inquire for pricing
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Collagen type III monoclonal antibody (1E7-D7/Col3) 

ELISA, IHC, WB | Print as PDF
 
BPD-CSI-007-01-02 200 µg 436.00 USD
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Collagen type XII monoclonal antibody (378D5) 

ELISA, IHC (FS), IP, WB | Print as PDF
 
ALX-803-309-R100 100 µl 431.00 USD
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Granzyme B (human) monoclonal antibody (B18.1) 

Purified from mouse ascites., Flow Cytometry, ICC, IHC (FS), IHC (PS), IP, WB | Print as PDF
 
ALX-804-121-C100 100 µg Purified 282.00 USD
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Granzyme B (human) monoclonal antibody (GrB7) 

IHC (PS), WB | Print as PDF
 
ALX-804-198-C050 50 µg 511.00 USD
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Active Proteases and Related Proteins

Collagen I, Rat Tail

  • High Purity, ≥90% (SDS-PAGE)
  • Sterile format for cell culture applications
  • Also available as a ready-to-use reagent for thin plate coating



Collagen I was tested in a cell proliferation assay. Increased attachment of cells on collagen coated coverslips was observed following culture.

 

Cathepsin B (human liver), (purified) 

Highly pure lysosomal protease
Purified from human liver., ≥95% (SDS-PAGE) | Print as PDF
 
BML-SE198-0025 25 µg 235.00 USD
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Cathepsin D (human liver), (purified) 

Isolated from human liver., ≥95% (SDS-PAGE) | Print as PDF
 
BML-SE199-0025 25 µg 230.00 USD
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Cathepsin F (human), (recombinant) 

Highly active
Produced in insect cells (secreted) as untagged proenzyme; activated during purification. Produced in a baculovirus expression system., ≥80% (SDS-PAGE) | Print as PDF
 
BML-SE568-0005 5 µg 390.00 USD
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Cathepsin G (human neutrophils), (purified) 

56645-49-9, Isolated from human neutrophils. Active enzyme. Negative for HbsAg, anti-HBc, anti-HCV, and anti-HIV-1 and -2., ≥95% by SDS-PAGE | Print as PDF
 
BML-SE283-0100 100 µg 267.00 USD
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Cathepsin H (human liver), (purified) 

Isolated from human liver. | Print as PDF
 
BML-SE200-0025 25 µg 286.00 USD
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Cathepsin K (human), (recombinant) 

Highly active cysteine protease
Produced in insect cells. Purified as full-length proenzyme (see Prod. No. BML-SE367), then auto-activated at low pH. Produced in a baculovirus expression system., ≥95% (SDS-PAGE) | Print as PDF
 
BML-SE553-0010 10 µg 422.00 USD
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Cathepsin L (human liver), (purified) 

Isolated from human liver. Negative for HbsAg, anti-HBc, anti-HCV, and anti-HIV-1 and -2., ≥95% by SDS-PAGE | Print as PDF
 
BML-SE201-0025 25 µg 418.00 USD
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Cathepsin S (human), (recombinant) 

Highly active
Produced in insect cells. Recombinant active cathepsin S cloned from human cDNA as full length proenzyme, auto-activated by incubation in pH 4.5 acetate buffer, and purified. Produced in a baculovirus expression system., ≥95% (SDS-PAGE) | Print as PDF
 
BML-SE453-0010 10 µg 388.00 USD
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Collagen I, rat tail 

Isolated from rat tail tendons., ≥90% (SDS-PAGE) | Print as PDF
 
ALX-522-435-0020 20 mg 71.00 USD
 
ALX-522-435-0100 100 mg 165.00 USD
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Collagen I, rat tail (thin plate coating) 

Isolated from rat tail tendons., ≥90% (SDS-PAGE) | Print as PDF
 
ALX-522-440-0050 50 ml 83.00 USD
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Elafin (human), (recombinant) 

Produced in yeast., ≥90% (HPLC, SDS-PAGE, MS) | Print as PDF
 
ALX-201-240-C100 100 µg 359.00 USD
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Granzyme A (human) 

Human cytotoxic granules of NK-92 cells. | Print as PDF
 
ALX-200-605-C010 10 µg 730.00 USD
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Granzyme A (human), (recombinant) 

Produced in E. coli. Active human granzyme A., ≥98% (SDS-PAGE) | Print as PDF
 
ALX-201-118-C010 10 µg 495.00 USD
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Granzyme B (human lymphocytes) 

Isolated from YT NK cell line using described methods. Active enzyme. | Print as PDF
 
ALX-200-602-C010 10 µg 696.00 USD
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Granzyme B (human), (recombinant) 

Produced in yeast. Recombinant human granzyme B (aa 21-247). | Print as PDF
 
BML-SE238-5000 5000 U 424.00 USD
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Granzyme K (human), (recombinant) 

Produced in E. coli. Active human granzyme K., ≥98% (SDS-PAGE) | Print as PDF
 
ALX-201-117-C010 10 µg 495.00 USD
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Neutrophil elastase (human), (purified) 

Isolated from human neutrophils. Active enzyme., ≥95% (SDS-PAGE). Although this is in highly purified form, and the source material tested negative for HbsAg, anti-HBc, anti-HCV, and anti-HIV-1 and -2, handle this product with all due precautions. | Print as PDF
 
BML-SE284-0100 100 µg 323.00 USD
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Procathepsin F (human), (recombinant) 

Produced in insect cells. Glycosylated procathepsin F. Produced in a baculovirus expression system. | Print as PDF
 
BML-SE541-0005 5 µg 345.00 USD
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Procathepsin K (human), (recombinant) 

Produced in insect cells. Full length glycosylated human procathepsin K (also known as cathepsin O or cathepsin O2) cloned from human cDNA. Produced in a baculovirus expression system., ≥95% (SDS-PAGE) | Print as PDF
 
BML-SE367-0010 10 µg 335.00 USD
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Procathepsin K (human), (recombinant) 

Produced in E. coli (aa 19-329). Methionine was introduced at aa 18 to create a new N-terminal sequence (MEEIL)., ≥95% (SDS-PAGE) | Print as PDF
 
ALX-201-239-C010 10 µg 231.00 USD
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Procathepsin V (human), (recombinant) (His-tag) 

Produced in insect cells. Recombinant glycosylated procathepsin V cloned from human cDNA and purified as full-length proenzyme. Produced in a baculovirus expression system., ≥90% | Print as PDF
 
BML-SE554-0010 10 µg 480.00 USD
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SLPI (human), (recombinant) (His-tag) 

Produced in insect cells. Human recombiinant SLPI (aa 25-132) is fused to a His-tag. Produced in a baculovirus expression system., ≥90% (SDS-PAGE), WB, in vitro Assay | Print as PDF
 
ADI-908-304-0010 10 µg 326.00 USD
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Protease Modulators

3,4 Dichloroisocoumarin 

Protease inhibitor
51050-59-0, ≥98% (Elemental Analysis) | Print as PDF
 
BML-PI110-0010 10 mg 256.00 USD
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Elastatinal 

Elastase inhibitor
51798-45-9, ≥98% (TLC) | Print as PDF
 
BML-PI103-0005 5 mg 88.00 USD
 
BML-PI103-0025 25 mg 349.00 USD
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SCREEN-WELL® Protease Inhibitor library 

HTS | Print as PDF
 
BML-2833-0500 1 Library 500 µl/well Inquire for pricing
 
BML-2833-0100 1 Library 100 µl/well Inquire for pricing
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Are you screening for protease inhibitors?

Our SCREEN-WELL® Protease Inhibitor Library includes 53 known protease inhibitors on a single 96-well plate.

 

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