Replaces Prod. #: ALX-200-314
Product Specification
| Source: | Isolated from human liver. Negative for HbsAg, anti-HBc, anti-HCV, and anti-HIV-1 and -2. |
| |
| UniProt ID: | P07711 (cathepsin L1) |
| |
| Purity: | ≥95% by SDS-PAGE |
| |
| Application Notes: | Useful for inhibitor screening, kinetic studies, and cleavage of substrates in vitro or in tissue culture. |
| |
| Shipping: | Shipped on Dry Ice |
| |
| Long Term Storage: | -80°C |
| |
| Scientific Background: | Cathepsin L is a lysosomal protease that can also be secreted from the cell and is involved in protein degradation, arthritis, and cancer. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Product Literature References
Cell penetrable, clickable and tagless activity-based probe of human cathepsin L: D. Dana, et al.; Bioorg. Chem.
85, 505 (2019),
Application(s): Activity assay,
Abstract;
Development of a highly potent, selective, and cell-active Inhibitor of cysteine cathepsin L-A hybrid design approach: D. Dana, et al.; Chem. Commun. (Camb.)
50, 10875 (2014),
Abstract;
