Collagenases (Matrix Metalloproteinase-1, MMP-8, and MMP-13) and gelatinases (MMP-2 and MMP-9) break down skin collagens, contributing to aging and wrinkling. Enzo offers high sensitivity colorimetric and fluorometric activity assays for screening collagenase and gelatinase inhibitors. Each assay is built using high purity active enzymes, and includes substrate, 96-well plate, and protocol.

Evaluate Extracellular Matrix Proteins and Metalloproteinases

Enzo provides a comprehensive portfolio of products for MMP research including activity assays, active enzymes, antibodies, and high purity MMP inhibitors to suit your research needs.

MMP Assays

Optimized Detection of MMP Inhibitors
Screen For Inhibitors of Specific MMPs
MMP Inhibitor Profiling Kit
MMP-Specific Screening Assays

Other MMP Products

Active MMPs and Proteins
MMP Inhibitors
MMP-specific Antibodies

Cathepsins, Granzymes and Elastases are involved in regulatory mechanisms in human skin and act as biomarkers for decreased skin elasticity due to UV exposure in photoaged human skin.

Monitor Protease Activity and Expression

Protease Assay Kits & Substrates
Protease-specific Antibodies
Active Proteases & Related Proteins
Protease Modulators & Screening Libraries

Assess Impact of Changes in Proliferation on Signs of Aging

Oxidative stress in response to aging and environmental stimuli can lead to tissue damage. Analysis of reactive oxygen species, mitochondrial dysfunction, lipid peroxidation and glutathione levels can provide an indication of the effectiveness of cosmetic and cosmeceutical formulations. Enzo offers a selection of assay kits that enable detection of oxidative stress from the nucleic acid level up through a complete whole cell analysis.

Determination of antioxidant capacity through oxidative stress biomarkers

ROS Kits, Probes & Inhibitors
Glutathione Detection Kits, Antibodies, Peptides & Modulators
Protein Carbonyl ELISA Kit
Lipid Peroxidation Detection Kits & Modulators
Cell Detoxification & Senescence
Proteostasis