Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

CD86 polyclonal antibody

ENZ-ABS705-0100 100 µg 474.00 USD
Do you need bulk/larger quantities?

Product Details

Alternative Name:LAB72, CD28LG2
Immunogen:Peptide corresponding to 17 amino acids near the center of human CD86. The immunogen is located within amino acids 160 - 210 of CD86.
UniProt ID:P42082
Species reactivity:Human
Applications:IF, IHC, WB
Purity Detail:Affinity chromatography purified via peptide column.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Use/Stability:Stable for at least 1 year after receipt when stored as recommended.
Handling:Avoid freeze/thaw cycles.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and is the ligand for two proteins at the cell surface of T cells, CD28 and the cytotoxic T-lymphocyte-associated protein 4 (CTLA-4). Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell and induces T-cell proliferation and cytokine production. CTLA-4 binding negatively regulates T-cell activation and diminishes the immune response. Blocking the CTLA-4-CD80/CD86 interaction has been shown to enhance T-cell functions in acute lymphoblastomic leukemia, suggesting that this pathway may be an attractive target for future cancer immunotherapy.
Regulatory Status:RUO - Research Use Only
CD86 polyclonal antibody WB
Western blot analysis of CD86 in (A) Daudi and (B) Raji cell lysate with CD86 antibody at 1 µg/mL.
CD86 polyclonal antibody IHC
Immunohistochemistry of CD86 in human lymph node tissue with CD86 antibody at 2 µg/ml.
CD86 polyclonal antibody IF
Immunofluorescence of CD86 in human lymph node tissue with CD86 antibody at 20 µg/ml. Red: CD86 Antibody (8681), Blue: DAPI staining.
Please mouse over
CD86 polyclonal antibody WB CD86 polyclonal antibody IHC CD86 polyclonal antibody IF

Product Toolbox


Certificate of Analysis


By target:
By biological activity:
CD86 Polyclonal antibody
By catalog section:


Technical Service
Customer Service