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Antibody-Based Detection of Cleaved Caspases

Caspase-8 (human) monoclonal antibody (12F5)

  • Recognizes procaspase-8 and active caspase-8. Detects procaspase-8 (p55/54), the intermediate cleavage products (p43/41) and the p18 active subunit of caspase-8 by Western blot
  • Does not cross-react with mouse caspase-8
  • Validated for Western blot, Immunoprecipation and Immunohistochemistry applications



(A) Schematic structure of caspase-8 and its cleavage products as detected by anti-caspase-8 (12F5). The antibody is directed against the p18 subunit and detects procaspase-8 (p55/54), the intermediate cleavage products of 43kD and 41kD and the p18 active subunit of caspase-8.
(B) Detection of Fas ligand-induced caspase-8 processing and activation in human Jurkat cells.

 

Caspase-1 polyclonal antibody 

ICC, IHC, IP, WB | Print as PDF
 
ALX-210-804-C100 100 µg 349.00 USD
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Caspase-1 (mouse) monoclonal antibody (1H11) 

ELISA, Flow Cytometry, WB | Print as PDF
 
ALX-804-530-C100 100 µg 385.00 USD
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Caspase-2 monoclonal antibody (11B4) 

IP, WB | Print as PDF
 
ALX-804-356-C100 100 µg 409.00 USD
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Caspase-3 polyclonal antibody 

Purified from rabbit serum., IHC (PS), WB | Print as PDF
 
ADI-AAP-113-D 50 µg 154.00 USD
 
ADI-AAP-113-F 200 µg 373.00 USD
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Caspase-3 monoclonal antibody (31A1067) 

IHC (FS), IHC (PS), WB | Print as PDF
 
ALX-804-305-C100 100 µg 345.00 USD
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Caspase-8 (human) monoclonal antibody (12F5) 

IHC (FS), IP, WB | Print as PDF
 
ALX-804-242-C100 100 µg 413.00 USD
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Caspase-8 (mouse) monoclonal antibody (1G12) 

ELISA, Flow Cytometry, ICC, WB | Print as PDF
 
ALX-804-447-C100 100 µg 304.00 USD
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