Cardiovascular Drug Discovery

Innovative Tools for Profiling Cardiac Toxicity
SCREEN-WELL® Cardiotoxicity Library
A focused collection of 131 compounds with defined and diverse cardiotoxicity. The library includes a variety of structurally and mechanistically different compound classes, as well as nontoxic controls. The compounds are dissolved in DMSO at 10mM and aliquoted into deep-well plates. The library is an essential tool for predictive toxicology screening and assay development.
- Arrhythmia
- Cardiomyocyte apoptosis
- Carditis
- Fibrosis
- Hypotension/Hypertension
- Ion Channel Blockage
- Mitochondrial Toxicity
- Non-cardiotoxic Controls
- Thrombosis