| Alternative Name: | MT1A, Metallothionein MGC32848, MT1S, MTC, Metallothionein 1A (functional) |
| |
| Clone: | UC1MT |
| |
| Host: | Mouse |
| |
| Isotype: | IgG1 |
| |
| Immunogen: | Cross-linked rabbit liver Metallothionein I and II. |
| |
| Source: | Purified from hybridoma tissue culture supernatant. |
| |
| Species reactivity: | Human, Mouse, Rat
Fish, Horse, Rabbit
|
| |
| Applications: | ELISA, IHC (PS), WB
|
| |
| Recommended Dilutions/Conditions: | Western Blot (1:1,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
| |
| Application Notes: | Detects a band of ~15kDa by Western blot. |
| |
| Purity Detail: | Protein G affinity purified. |
| |
| Formulation: | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
| |
| Shipping: | Blue Ice |
| |
| Long Term Storage: | -20°C |
| |
| Scientific Background: | Metallothioneins (MTs) are a class of ubiquitous, low molecular weight, cysteine-rich, metal binding proteins that function in the metabolism of zinc and copper. MT protects against exposure to toxic metals such as mercury and cadmium as well as a variety of other stress conditions. There are four mammalian MT isoforms: MT-I, -II, -III, -IV, each of which is encoded by individual genes. MT expression is induced by heavy metal cations, starvation, elevated temperature, lipopolysaccharide, inflammatory cytokines, free radicals, and ionizing radiation. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
