Phytoestrogen. Inhibits P-glycoprotein.
Product Details
| Alternative Name: | (3R,4R)-Dihydro-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]- 2(3H)-furanone |
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| Formula: | C20H22O6 |
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| MW: | 358.4 |
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| Source: | Synthesized from (-)-Matairesinol-4-O-glucoside (Prod. No. ALX-350-403). |
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| CAS: | 580-72-3 |
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| Purity: | ≥97% (HPLC) |
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| Identity: | Identity determined by MS, 1H- and 13C-NMR. |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in methanol, 100% ethanol, ethyl acetate, dichloroethane or ether; slightly soluble in water. |
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| Shipping: | Ambient |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Inhibition of P-glycoprotein and multidrug resistance protein 1 by dietary phytochemicals: T. Nabekura, et al.; Cancer Chemother. Pharmacol.
62, 867 (2008),
Abstract;
Phytoestrogens and phytoestrogen metabolites differentially modulate immune parameters in human leukocytes: S. Gredel, et al.; Food Chem. Toxicol.
46, 3691 (2008),
Abstract;
Antimicrobiological activity of lignan: effect of benzylic oxygen and stereochemistry of 2,3-dibenzyl-4-butanolide and 3,4-dibenzyltetrahydrofuran lignans on activity: K. Akiyama, et al.; Biosci. Biotechnol. Biochem.
71, 1745 (2007),
Abstract;
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