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Native Toxins and Antigens for Diagnostics Development

Bacterial protein toxins are among the most powerful human poisons known and can retain high activity at very high dilutions. Venoms and toxins often specifically interact with a macromolecular target in the body, and as such are important tools in studying receptors, ion channels, and enzymes.

Antigens are widely used for immunodiagnostic assays such as ELISA, but recombinant proteins can often provide decreased sensitivity and specificity. Enzo Life Sciences offers a broad range of native bacterial and viral antigens to fill this need for the research and in vitro diagnostics markets. Wherever practical, our antigens are isolated and purified from culture. In cases where antigen yield may be very low, the antigens are produced using the latest mammalian expression systems.

Typical applications include:

  • Serology-based ELISA assays
  • Positive controls
  • Cytotoxicity testing
  • Immunogens (toxoids) to illicit the optimum immune response

Featured Products

Native Viral Antigens. Optimal Antigenicity.

Medically relevant viral recombinant proteins produced in bacteria, yeast or insect cells seldom undergo correct post-translational modification due to the expression host lacking the same cellular machinery as the natural host. By contrast, proteins produced entirely in human cell lines ensure that the resultant antigens are expressed to a high level, are in their native folded state, and possess all relevant post-translational modifications. This advanced approach offers products which deliver optimal antigenicity for use in vaccine development and serological based diagnostic assays.
  • Higher specificity and sensitivity
  • Minimal lot-to-lot variation
  • Reproducible scale-up for bulk quantities
  • Lyophilized format for extended shelf-life
 

Featured Products

C. trachomatis native antigen 

Cell lysate ideal for use as a broad positive control
From Chlamydia trachomatis, serotype LGV2 strain 434. Inactivated by heat treatment and 0.05% Triton X-100., ELISA, Positive control | Print as PDF
 
ALX-630-124-1000 1 ml 599.00 USD
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Adenovirus type 5 hexon protein 

From adenovirus type 5., ≥95% (SDS-PAGE), ELISA, Antibody capture, Positive control | Print as PDF
 
ALX-630-120-0100 100 µg 252.00 USD
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Adenovirus type 40 antigen 

From adenovirus type 40. Inactivated by 2 hours at 54°C., ≥99%, ELISA, Antibody capture, Immunogen, LINE assay | Print as PDF
 
ALX-630-121-0100 100 µg 252.00 USD
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Astrovirus type 1 antigen 

Concentrated source of Astrovirus particles and proteins
From astrovirus type 1, strain A88/2 Newcastle. Inactivated by b-propiolactone 0.1% and 4 hours at 32°C., ELISA, Positive control | Print as PDF
 
ALX-630-122-0200 200 µl 599.00 USD
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Bordetella pertussis toxin 

High purity toxin with minimal lot-to-lot variation
70323-44-3, From Bordetella pertussis, strain NCTC 10739., ≥98%, ELISA, Antibody capture, Cytotoxicity studies, LINE assay | Print as PDF
 
BML-G101-0050 50 µg 284.00 USD
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Pertussis toxin (Bordetella pertussis) 

Ultra-pure pertussis toxin delivering optimal antigenicity
82248-93-9, From Bordetella pertussis., ≥99% | Print as PDF
 
BML-G100-0050 50 µg 385.00 USD
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Bordetella pertussis FHA 

From Bordetella pertussis, strain NCTC 10739., ≥98% (SDS-PAGE), ELISA, Antibody capture, LINE assay | Print as PDF
 
ALX-630-123-0100 100 µg Inquire for pricing
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C. difficile toxin A 

From Clostridium difficile, strain VPI10463., ≥95% (SDS-PAGE), ELISA, Antibody capture, Cytotoxicity studies, LINE assay | Print as PDF
 
BML-G140-0050 50 µg 315.00 USD
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C. difficile toxin A from ribotype 027, (native) 

Highly purifed preparation from hypervirulent ribotype 027
From Clostridium difficile, strain R20291 (Stoke Mandeville) ribotype 027., ≥95% (SDS-PAGE), ELISA, Antibody capture, Cytotoxicity studies, LINE assay | Print as PDF
 
ENZ-PRT108-0002 2 µg 638.00 USD
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C. difficile toxin B 

From Clostridium difficile, strain VPI10463., ≥95% (SDS-PAGE), ELISA, Antibody capture, Cytotoxicity studies, LINE assay | Print as PDF
 
BML-G150-0050 50 µg 599.00 USD
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C. difficile toxoid A 

From Clostridium difficile, strain VPI10463. Inactivated by formaldehyde., ≥95% (SDS-PAGE), ELISA, Antibody capture, Cytotoxicity studies, Immunogen, LINE assay | Print as PDF
 
BML-G145-0050 50 µg 347.00 USD
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C. difficile toxoid B 

From Clostridium difficile, strain VPI10463. Inactivated by formaldehyde., ≥95% (SDS-PAGE), ELISA, Antibody capture, Cytotoxicity studies, Immunogen, LINE assay | Print as PDF
 
BML-G155-0050 50 µg 615.00 USD
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Cholera toxin (Vibrio cholerae), (azide free) 

G protein activator
9012-63-9, From Vibrio cholerae. | Print as PDF
 
BML-G117-0001 1 mg 189.00 USD
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Cholera toxin B subunit (Vibrio cholerae) 

G protein activator
131096-89-4, From Vibrio cholerae. | Print as PDF
 
BML-G125-0001 1 mg 600.00 USD
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CMV native antigen 

From cytomegalovirus, strain AD169. Inactivated by 0.2% Triton X-100., ≥95%, ELISA, Antibody capture, Positive control | Print as PDF
 
ALX-630-125-0100 100 µg 425.00 USD
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Dengue NS1 ST1, (recombinant) 

Dengue virus NS1 protein serotype 1 presented in its native folded state with all post-translational modifications to deliver optimal antigenicity.
Produced in HEK 293 cells. Dengue Viral NS1 Serotype 1 (DENV1-NS1) from strain Nauru/Western Pacific/1974., ≥95% (SDS-PAGE), ELISA, Antibody capture, LINE assay, Vaccine research | Print as PDF
 
ENZ-PRT104-0100 100 µg 204.00 USD
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Dengue NS1 ST2, (recombinant) 

Dengue virus NS1 protein serotype 2 presented in its native folded state with all post-translational modifications to deliver optimal antigenicity.
Produced in HEK 293 cells. Dengue Viral NS1 Serotype 2 (DENV2-NS1) from strain Thailand/16681/84., ≥95% (SDS-PAGE), ELISA, Antibody capture, LINE assay, Vaccine research | Print as PDF
 
ENZ-PRT105-0100 100 µg 204.00 USD
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Dengue NS1 ST3, (recombinant) 

Dengue virus NS1 protein serotype 3 presented in its native folded state with all post-translational modifications to deliver optimal antigenicity.
Produced in HEK 293 cells. Dengue Viral NS1 Serotype 3 (DENV1-NS1) from strain Sri Lanka D3/H/IMTSSA-SRI/2000/1266., ≥95% (SDS-PAGE), ELISA, Antibody capture, LINE assay, Vaccine research | Print as PDF
 
ENZ-PRT106-0100 100 µg 561.00 USD
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Dengue NS1 ST4, (recombinant) 

Dengue virus NS1 protein serotype 3 presented in its native folded state with all post-translational modifications to deliver optimal antigenicity.
Produced in HEK 293 cells. Dengue Viral NS1 Serotype 4 (DENV4-NS1) from strain Dengue virus 4 Dominica/8146 69/1981., ≥95% (SDS-PAGE), ELISA, Antibody capture, LINE assay, Vaccine research | Print as PDF
 
ENZ-PRT107-0100 100 µg 648.00 USD
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Yellow Fever NS1, (recombinant) 

Yellow Fever virus NS1 protein presented in its native folded state with all post-translational modifications to deliver optimal antigenicity.
Produced in HEK 293 cells. Yellow Fever Virus NS1 protein from strain 17D., ≥95% (SDS-PAGE), ELISA, Antibody capture, LINE assay, POC diagnostic, Vaccine research | Print as PDF
 
ENZ-PRT109-0100 100 µg 250.00 USD
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HSV-1 native antigen 

From herpes simplex virus type 1. Inactivated by 0.1% Triton X-100., ≥80%, ELISA, Antibody capture, Positive control | Print as PDF
 
ALX-630-126-0200 200 µl 457.00 USD
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HSV-2 native antigen 

From herpes simplex virus type 2, strain G. Inactivated by 0.1% Triton X-100., ≥80%, ELISA, Antibody capture, Positive control | Print as PDF
 
ALX-630-127-0200 200 µl 457.00 USD
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M. pneumoniae native antigen 

From Mycoplasma pneumoniae, strain FH. Inactivated by detergent treatment., ≥95%, ELISA, Antibody capture, Positive control | Print as PDF
 
ALX-630-128-0100 100 µg 157.00 USD
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N. gonorrhoeae native antigen 

Bacterial lysate ideal for use as a broad positive control
From Neisseria gonorrhoeae, strain ATCC 19424. Inactivated by 3 hours at 56°C., ≥99%, ELISA, Antibody capture, Cytotoxicity studies, Immunogen, LINE assay | Print as PDF
 
ALX-630-129-1000 1 ml 552.00 USD
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T. vaginalis native antigen 

Cell lysate ideal for use as a broad positive control
From Trichomonas vaginalis, strain C-1:NIH. Inactivated by freezing/thawing in water., ≥99%, ELISA, Antibody capture, Cytotoxicity studies, Immunogen, LINE assay | Print as PDF
 
ALX-630-130-1000 1 ml 552.00 USD
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For Research Use Only. Not for use in diagnostic procedures.
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