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Cholera toxin B subunit (Vibrio cholerae)

G protein activator
BML-G125-0001 1 mg Inquire for pricing
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Product Details

Source:From Vibrio cholerae.
UniProt ID:P01556
Shipping:Ambient Temperature
Long Term Storage:+4°C
Scientific Background:The B subunit of cholera toxin attaches the native toxin to eukaryotic cell surfaces and facilitates the translocation of the A subunit. It does not possess any intrinsic ADP-ribosyltransferase activity. The high affinity and specificity of the B subunit for ganglioside GM1 makes it a novel tool for probing the involvement of GM1 on growth and differentiation of neuronal and other cells.
Regulatory Status:RUO - Research Use Only

Product Literature References

Blocking GARP-mediated activation of TGF-β1 did not alter innate or adaptive immune responses to bacterial infection or protein immunization in mice: M. Gaignage, et al.; Cancer Immunol. Immunother. 71, 1851 (2022), Abstract;
The Effect of Solar Irradiated Vibrio cholerae on the Secretion of Pro-Inflammatory Cytokines and Chemokines by the JAWS II Dendritic Cell Line In Vitro: C.C. Ssemakalu, et al.; PLoS One 10, e0130190 (2015), Application(s): Cell Culture, Abstract; Full Text

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