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Additional Safety & Toxicity Testing

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Whole Cell Analysis of Cytotoxic Compounds

Toxicity assessment determines whether a drug or compound induces inflammatory or cytotoxic processes such as apoptosis, cell proliferation, and oxidative stress. Enzo offers a diverse collection of assays for analysis of cell viability and cytotoxicity.

 

MITO-ID® Membrane Potential Cytotoxicity Assay Kit

A real-time mitochondrial membrane potential assay with superior sensitivity

  • 10x more sensitive than JC-1 with superior aqueous solubility
  • Photostable dual-emission dye
  • No-wash/no-medium removal
  • Separate Mito-ID® Red/Green assays available for detection of mitochondrial mass
  • Suitable for high-throughput applications

High-throughput Analysis of Mitotoxicity


Detect mitochondrial perturbations with 10 times
more sensitivity than JC-1.

 

LYSO-ID® Red Cytotoxicity Kit

A rapid, quantitative and HTS-compatible live cell cytotoxicity assay

  • Lyso-ID® dye rapidly partitions into cells and labels acidic organelles
  • Only commercial assay available that allows for long-term cell monitoring of cytotoxic effects
  • Multi-well, HTS-compatible assay with rapid 10-15 minute dye incubation

Monitor Dysfunction of Lysosomal Degradation


Drug-induced lysosome accumulation in U-2 OS
cells was evaluated using Verapamil (200 μM)
and Lyso-ID® Red dye.

 

CYTO-ID® Autophagy detection kit 

A no-transfection, quantitative assay for monitoring autophagy in live cells
Flow Cytometry, Fluorescence microscopy, Fluorescent detection, HTS | Print as PDF
 
ENZ-51031-0050 50 tests 205.00 USD
 
ENZ-51031-K200 200 tests 420.00 USD
Do you need bulk/larger quantities?
 

GFP-CERTIFIED® Apoptosis/Necrosis detection kit 

Multiplex assay that distinguishes between  healthy, early apoptotic, late apoptotic and necrotic cells, compatible with GFP and other green fluorescent probes
Flow Cytometry, Fluorescence microscopy, Fluorescent detection | Print as PDF
 
ENZ-51002-25 25 assays 157.00 USD
 
ENZ-51002-100 100 assays 371.00 USD
Do you need bulk/larger quantities?
 

LYSO-ID® Red cytotoxicity kit (GFP-CERTIFIED®) 

A Rapid, Quantitative and HTS‐compatible Live Cell Cytotoxicity Assay 
Fluorescence microscopy, Fluorescent detection | Print as PDF
 
ENZ-51015-KP002 1 Kit 335.00 USD
Do you need bulk/larger quantities?
 

MITO-ID® Membrane potential cytotoxicity kit  

A Real-time Mitochondrial membrane Potential Assay with Superior Sensitivity
HTS, Microplate | Print as PDF
 
ENZ-51019-KP002 1 Kit 253.00 USD
Do you need bulk/larger quantities?
 

MITO-ID® Membrane potential detection kit  

The only assay that monitors energetic status using a simple mix-and-read, no-wash protocol
Flow Cytometry, Fluorescence microscopy, Fluorescent detection, HTS | Print as PDF
 
ENZ-51018-0025 25 tests 161.00 USD
 
ENZ-51018-K100 100 tests 462.00 USD
Do you need bulk/larger quantities?
 

NUCLEAR-ID® Green chromatin condensation detection kit  

A highly permeable green-emitting  dye for enhanced detection of apoptosis-induced chromatin condensation
Flow Cytometry, Fluorescence microscopy, Fluorescent detection | Print as PDF
 
ENZ-51021-K200 1 Kit 284.00 USD
Do you need bulk/larger quantities?
 

NUCLEAR-ID® Blue/Green cell viability reagent 

Distinguishes between live vs dead cells in a single reagent.
≥93% (HPLC), Flow Cytometry, Fluorescence microscopy, Fluorescent detection | Print as PDF
 
ENZ-53004-C100 100 µl 245.00 USD
Do you need bulk/larger quantities?
 

NUCLEAR-ID® Blue/Red cell viability reagent (GFP-CERTIFIED®) 

Distinguishes between live vs dead cells in a single reagent.
≥93% (HPLC), Flow Cytometry, Fluorescence microscopy, Fluorescent detection | Print as PDF
 
ENZ-53005-C100 100 µl 240.00 USD
Do you need bulk/larger quantities?
 

NUCLEAR-ID® Red/Green cell viability reagent 

Distinguishes between live vs dead cells in a single reagent
≥93% (HPLC), Flow Cytometry, Fluorescence microscopy, Fluorescent detection | Print as PDF
 
ENZ-53006-C100 100 µl 245.00 USD
Do you need bulk/larger quantities?
 

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