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IL-1F5 (mouse), (recombinant)

 
ALX-522-144-C050 50 µg 329.00 USD
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Product Specification

Alternative Name:Interleukin-1 family member 5, IL-1δ, Interleukin-1δ
 
MW:~16kDa
 
Source:Produced in E. coli (aa 2-156).
 
UniProt ID:Q9QYY1
 
Concentration:1mg/ml after reconstitution.
 
Formulation:Lyophilized. Contains PBS.
 
Purity:≥95% (SDS-PAGE)
 
Endotoxin Content:<0.1EU/µg purified protein (LAL test; Associates of Cape Cod).
 
Reconstitution:Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 6 months after receipt when stored at -20°C.
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
 
Scientific Background:IL-1F5, F6, F8 and F9 are members of the family of IL-1 (IL-1α/β, IL-18, IL-33). IL-1F6, IL-1F8 and IL-1F9 activate the NF-κB and MAPK pathways through the IL-Rrp2 and IL-1RAcP receptor complex leading to the production of IL-6 and IL-8. Agonistic activation of the IL-1F6, F8 and F9 is counterbalanced by the inhibitory activity of IL-1F5. These interleukins are mainly expressed in skin keratinocytes and internal epithelial tissues exposed to pathogenic bacteria suggesting a role in immune signalling and inflammation. IL-F5, F6 and F9 as well as the receptor IL-1Rrp2 are increased in psoriasis.
 

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IL-1F5 (human), (recombinant) 

Produced in E. coli (aa 1-155)., ≥95% (SDS-PAGE) | Print as PDF
 
ALX-522-127-C050 50 µg 327.00 USD
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