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GITR (human):Fc (human), (recombinant)

 
ALX-522-061-C050 50 µg 408.00 USD
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Product Specification

Alternative Name:AITR, TNFRSF 18, Glucocorticoid-induced TNFR-related protein, Activation-inducible TNFR family receptor
 
MW:~47kDa (SDS-PAGE).
 
Source:Produced in HEK 293 cells. The cysteine-rich region of human GITR (AITR) (aa 26-161) is fused to the Fc portion of human IgG1.
 
UniProt ID:Q9Y5U5
 
Quantity:50µg
 
Concentration:1mg/ml after reconstitution.
 
Formulation:Lyophilized. Contains PBS.
 
Purity:≥90% (SDS-PAGE)
 
Endotoxin Content:<0.1EU/µg purified protein (LAL test; Bio Whittaker).
 
Specificity:Binds human GITRL (AITRL).
 
Applications:ELISA
 
Application Notes:ELISA: binds to human GITRL.
 
Reconstitution:Reconstitute with 50µl sterile distilled water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:-20°C
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 6 months after receipt when stored as recommended.
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
 

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Product Literature References

Identification of glucocorticoid-induced TNF receptor-related protein ligand on keratinocytes: ligation by GITR induces keratinocyte chemokine production and augments T-cell proliferation: A.M. Byrne, et al.; J. Invest. Dermatol. 129, 2784 (2009), Abstract; Full Text

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