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Omentin 1 polyclonal antibody (AT117)

 
ALX-210-941-C100 100 µg 260.00 USD
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Product Specification

Alternative Name:Endothelial lectin HL-1, Intelectin-1, Intestinal lactoferrin receptor, Galactofuranose-binding lectin
 
Host:Rabbit
 
Immunogen:Recombinant human omentin 1 (intelectin-1) (aa 17-231).
 
UniProt ID:Q8WWA0
 
Species reactivity:Human, Mouse, Rat
 
Crossreactivity:Cross-reacts with human omentin 2.
 
Applications:IP, WB
 
Recommended Dilutions/Conditions:Immunoprecipitation (1:100)
Western Blot (1:500)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein A-affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
 
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Scientific Background:Omentin 1 (also named intelectin-1, endothelial lectin HL-1 and intestinal lactoferrin receptor) has been identified as a visceral fat (or omental fat) depot-specific adipokine. Omentin 1 is a secreted protein of ~38 kDa containing a fibrinogen-related domain. Omentin 1 is highly expressed in the omental fat, and much less in intestine, lung and heart. Addition of recombinant omentin in vitro did not affect basal, but enhanced insulin-stimulated glucose uptake in subcutaneous as well as in omental human adipocytes. Omentin 1 triggers AKT signalling in the absence of insulin.
 

General Literature References

Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action: R.Z. Yang, et al.; Am. J. Physiol. Endocrinol. Metab. 290, E1253 (2006), Abstract;

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Omentin 1 (human), (recombinant) 

Produced in HEK 293 cells. Human omentin 1 (intelectin-1) (aa 17-313) is fused at the N-terminus to a FLAG®-tag., ≥95% (SDS-PAGE) | Print as PDF
 
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Omentin 1 (human) monoclonal antibody (Saly-1) 

Purified from concentrated hybridoma tissue cell culture supernatant., ELISA, IHC (PS), WB | Print as PDF
 
ALX-804-850-C100 100 µg 379.00 USD
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