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Ponatinib

Potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src



ENZ-CHM179-0005	5 mg	86.00 USD

ENZ-CHM179-0010	10 mg	124.00 USD
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Ponatinib is a potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC₅₀ values of 0.37, 1.1, 1.5, 2.2 and 5.4 nM respectively.

Alternative Name:	AP 24534, 3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide

Formula:	C₂₉H₂₇F₃N₆O

MW:	532.6

CAS:	943319-70-8

Purity:	≥98% (HPLC)

Identity:	Determined by EM-MS, NMR

Appearance:	Yellow powder.

Solubility:	Soluble in DMSO (107mg/ml) or ethanol (107mg/ml).

Shipping:	Ambient Temperature

Short Term Storage:	+4°C

Long Term Storage:	-20°C

Regulatory Status:	RUO - Research Use Only