| BPD-ABS-004-22-04 | 400 µg | 1,527.00 USD |  |
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| BPD-ABS-004-22-1 | 1 mg | 2,991.00 USD | |
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| Alternative Name: | C9 esterase |
| Clone: | 22 |
| Host: | Mouse |
| Isotype: | IgG1κ |
| Immunogen: | Human complement factor C9. |
| UniProt ID: | P02748 |
| Species reactivity: | Human |
| Applications: | ELISA, IF, IHC, WB |
| Application Notes: | Detects a band of ~71kDa by Western blot. |
| Purity Detail: | Protein A/G-affinity purified. |
| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Short Term Storage: | +4°C |
| Scientific Background: | Complement factor C9 is a 71kDa single-chain ellipsoid a-globular molecule of 558 amino acids including a leader sequence of 20 amino acids. C9 binds the C5b8 complex on membranes and has the unique function of forming tubular structures containing between 12 and 18 monomers, closely resembling the membrane attack complex (MAC). The primary site of synthesis is hepatocytes; secondary sites are monocytes, fibroblasts and glial cells. The normal level of C9 in plasma is 60 µg/ml, and the level is upregulated from hepatocytes by IFN-γ. |
| Regulatory Status: | RUO - Research Use Only |
