Product Details
| Alternative Name: | β-Secretase, Memapsin-2, Asp-2, Beta-site APP-cleaving enzyme-1 |
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| MW: | 45 kDa |
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| Source: | Produced in E. coli. Active soluble BACE1. |
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| UniProt ID: | P56817 |
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| Application Notes: | Useful tool to study enzyme kinetics, cleave target substrates, and screen for inhibitors. |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Scientific Background: | BACE1 is an aspartic protease involved in Alzheimer’s disease and cancer. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Abnormal platelet amyloid-β protein precursor (AβPP) metabolism in Alzheimer's disease: identification and characterization of a new AβPP isoform as potential biomarker: V. Jelic, et al.; J. Alzheimers Dis.
35, 285 (2013),
Abstract;
Development of a specific ELISA to measure BACE1 levels in human tissues: A. Gonzales, et al.; J. Neurosci. Methods
202, 70 (2011),
Abstract;
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