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Benzylimidazole

Inducer of cytochrome P450
 
BML-EI162-0005 5 g Inquire for pricing
 
BML-EI162-0001 1 g Inquire for pricing
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Induces various cytochrome P-450 isozymes including lauric acid hydroxylase. Decreases plasma triglyceride levels in rats. Inhibits thromboxane A2 synthase.

Product Specification

Formula:C10H10N2
 
MW:158.2
 
CAS:4238-71-5
 
Purity:≥97% (GC, Titration)
 
Appearance:White solid.
 
Solubility:Soluble in DMSO or ethanol.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Regulatory Status:RUO - Research Use Only
 
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Product Literature References

Involvement of testosterone in the induction of hepatic microsomal cytochrome P-450 2B1/2 (P-450 2B1/2) by 1-benzylimidazole in male and female rats: sex-differentiated induction of P-450 2B1/2 species: Y. Kobayashi, et al.; Biochim. Biophys. Acta. 1200, 11 (1994), Abstract;
N-benzylimidazole, a potent inducer of rat liver enzymes involved in mutagenic activation of various carcinogens: Y. Mori, et al.; Mutat. Res. 302(2), 129 (1993), Abstract;
Effect of 1-benzylimidazole on cytochromes P-450 induction and on the activities of epoxide hydrolases and UDP-glucuronosyltransferases in rat liver: J. Magdalou, et al.; Biochem. Pharmacol. 37, 3297 (1988), Abstract;
Carbon tetrachloride-induced eicosanoid synthesis and enzyme release from rat peritoneal leucocytes: T. J. Lynch, et al.; Biochem. Pharmacol. 34, 1515 (1985), Abstract;

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