Product Details
| Alternative Name: | OX40L, TNFSF 4, CD252 |
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| Clone: | MGP34 |
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| Host: | Rat |
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| Isotype: | IgG2c |
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| Immunogen: | Rat cells stably overexpressing mouse CD134L (OX40L). |
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| UniProt ID: | P43488 |
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| Species reactivity: | Mouse
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| Crossreactivity: | Does not cross-react with human CD134L. |
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| Applications: | Flow Cytometry, IP, WB, FUNC
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| Application Notes: | Functional Application: blocks binding of CD134L to CD134 |
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| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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| Use/Stability: | Stable for at least 1 year after receipt when stored as recommended. |
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| Handling: | Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Figure: Flow cytometry using MAb to CD134L (mouse) (blocking) (MGP34) (Prod. No.
ALX-804-138).
Method: Rat TART-gp34 cells (5x10
5) expressing surface mouse OX40L vector (thick line) or TART-1 parental cells (dotted line), were incubated on ice for 30 min. in 50µl FACS buffer (PBS, 5% fetal calf serum, 0.02% azide) containing 1µg/ml of MAb to CD134L (mouse) (blocking) (MGP34). After washing in FACS buffer, FITC-conjugated antibody to rat IgG (Prod. No.
ALX-211-051) was added. Cells were incubated on ice for 30 min., washed and then analyzed by flow cytometry."
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Product Literature References
Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand: K. Murata, et al.; J. Exp. Med.
191, 365 (2000),
Abstract;
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