Replaces Prod. #: BML-T111
Binds to polymeric actin with high affinity. Stabilizes filaments and decreases concentration of monomeric actin.
Product Details
| Alternative Name: | EL-Phalloidin |
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| Formula: | C35H48N8O11S |
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| MW: | 788.9 |
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| Source: | Isolated from Amanita phalloides mushrooms. |
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| CAS: | 17466-45-4 |
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| MI: | 14: 7196 |
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| Purity: | ≥90% (HPLC) |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in DMF, DMSO, 100% ethanol (10mg/ml), 100% methanol, and water (1mg/ml, warm). |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
An automated and highly sensitive chemiluminescence immunoassay for diagnosing mushroom poisoning: J. Zhu, et al.; Front. Chem.
9, 813219 (2021),
Abstract;
Full Text
Highly sensitive determination of amanita toxins in biological samples using β-cyclodextrin collaborated molecularly imprinted polymers coupled with ultra-high performance liquid chromatography tandem mass spectrometry: L. Tan, et al.; J. Chromatogr. A
1630, 461514 (2020),
Abstract;
Lateral flow immunoassay (LFIA) for the detection of lethal amatoxins from mushrooms: C.S. Beyer, et al.; PLoS One
15, E0231781 (2020),
Abstract;
Full Text
A rapid extraction method combined with a monoclonal antibody-based immunoassay for the detection of amatoxins: C.S. Beyer, et al.; Toxins
11, 724 (2019),
Abstract;
Full Text
A new conjugation method used for the development of an immunoassay for the detection of amanitin, a deadly mushroom toxin: C.S. Beyer, et al.; Toxins
10, 265 (2018),
Abstract;
Full Text
Position and orientation of phalloidin in F-actin determined by X-ray fiber diffraction analysis: T. Oda, et al.; Biophys. J.
88, 2727 (2005),
Abstract;
Effects of cytochalasin and phalloidin on actin: J.A. Cooper; J. Cell. Biol.
105, 1473 (1987), (Review),
Abstract;
What we have learned from phalloidin: M. Frimmer; Toxicol Lett.
35, 169 (1987),
Abstract;
Phalloidin-induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth: J. Wehland, et al.; PNAS
74, 5613 (1977),
Abstract;
Interaction of actin with phalloidin: polymerization and stabilization of F-actin: P. Dancker, et al.; Biochim. Biophys. Acta
400, 407 (1975),
Abstract;
Interaction of phalloidin with actin: A.M. Lengsfeld, et al.; PNAS
71, 2803 (1974),
Abstract;
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