Produced upon hormonal stimulation of cells. Precursor is postulated to be Ins(1,3,4,5)P4 . For the enantiomer Ins(1,3,6)P3, see Prod. No. ALX-307-050
Product Specification
| Alternative Name: | Ins(1,3,4)P3 . 6K |
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| Formula: | C6H9O15P3 . 6K |
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| MW: | 414.1 . 234.6 |
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| CAS: | 140385-74-6 |
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| Purity: | ≥98% (HPLC) |
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| Identity: | Identity determined by 1H-NMR, 31P-NMR and MS. |
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| Appearance: | White to off-white powder. |
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| Solubility: | Soluble in water. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Handling: | Hygroscopic. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate: X. Yang, et al.; J. Biol. Chem.
274, 18973 (1999),
Abstract;
Full Text
Calcium modulates the generation of inositol 1,3,4-trisphosphate in human platelets by the activation of inositol 1,4,5-trisphosphate 3-kinase: J.L. Daniel, et al.; Biochem. J.
253, 789 (1988),
Abstract;
Pathway for inositol 1,3,4-trisphosphate and 1,4-bisphosphate metabolism: R.C. Inhorn, et al.; PNAS
84, 2170 (1987),
Abstract;
The metabolism of inositol 1,3,4-trisphosphate to inositol 1,3-bisphosphate: V.S. Bansal, et al.; J. Biol. Chem.
262, 9444 (1987),
Abstract;
Full Text
Interconversion of inositol (1,4,5)-trisphosphate to inositol (1,3,4,5)- tetrakisphosphate and (1,3,4)-trisphosphate in permeabilized adrenal glomerulosa cells is calcium-sensitive and ATP-dependent: M.F. Rossier, et al.; BBRC
139, 259 (1986),
Abstract;
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