Product Details
| Alternative Name: | Angiopoietin-like protein 3, Angiopoietin-5, ANG-5 |
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| Source: | Produced in HEK 293 cells. The signal peptide and the coiled-coil domain of mouse ANGPTL3 (angiopoietin-like protein 3) (aa 1-206) are fused at the C-terminus to a His-tag. |
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| UniProt ID: | Q9R182 |
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| Concentration: | 0.3mg/ml |
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| Formulation: | Liquid. 0.2μm-filtered solution in PBS. |
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| Purity: | ≥90% (SDS-PAGE) |
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| Endotoxin Content: | <1EU/µg protein (LAL-test). |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Working aliquots are stable for up to 3 months when stored at -20°C. |
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| Handling: | Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C. |
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| Regulatory Status: | RUO - Research Use Only |
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Figure: SDS-PAGE of ANGPTL3 (Coiled-coil Domain) (mouse) (recombinant) (His) (Prod. No.
ALX-201-412)."
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General Literature References
Angiopoietin-like proteins: potential new targets for metabolic syndrome therapy: Y. Oike, et al.; Trends Mol. Med.
11, 473 (2005),
Abstract;
Differential regulation and properties of angiopoietin-like proteins 3 and 4: H. Ge, et al.; J. Lipid Res.
46, 1484 (2005),
Abstract;
ANGPTL3 is increased in both insulin-deficient and -resistant diabetic states: K. Inukai; Biochem. Biophys. Res. Commun.
317, 1075 (2004),
Abstract;
Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes: M. Shimamura, et al. ; Biochem. Biophys. Res. Commun.
301, 604 (2003),
Abstract;
ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase: T. Shimizugawa, et al.; J. Biol. Chem.
27, 33742 (2002),
Abstract;
Full Text
Identification of a mammalian angiopoietin-related protein expressed specifically in liver: D. Conklin, et al.; Genomics
62, 477 (1999),
Abstract;
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