| ADI-AAP-210-D | 50 µg | 227.00 USD |  |
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| ADI-AAP-210-F | 200 µg | 433.00 USD | |
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| Alternative Name: | MORT1, Fas (TNFRSF6)-associated via death domain |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to a portion of human FADD. |
| UniProt ID: | Q13158 |
| Source: | Purified from rabbit serum. |
| Species reactivity: | Human, Rat Monkey |
| Applications: | ICC, IHC (PS), WB |
| Recommended Dilutions/Conditions: | Western Blot (1:1,000, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~28kDa by Western blot. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Fas-associating death domain containing protein (FADD)/MORT1 serves as a signal transducer of Fas-induced apoptosis. Through its amino-terminal death effector domain (DED), FADD binds to cytosolic proteins such as TRADD, a cytosolic death domaincontaining protein that asssociates with the cytosolic portion of TNF receptor, or MACH/FLICE/caspase-8, a protease with sequence homology to ICE-CED-3 protease family, in order to transduce the death signal. |
| Regulatory Status: | RUO - Research Use Only |
Goat anti-rabbit IgG, polyclonal antibody (HRP conjugate) |
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| ELISA, IHC, WB | Print as PDF | ||||||
| ADI-SAB-300-J | 1 ml | 130.00 USD | |
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HeLa, (cell lysate) |
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| Human, WB | Print as PDF | ||||||
| ADI-LYC-HL100-F | 200 µg | 119.00 USD | |
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