Proteostasis

Comprehensive Solutions For Complex Protein Networks

Protein homeostasis or ‘proteostasis’ is the process that regulates proteins within the cell in order to maintain the health of both the cellular proteome and the organism itself.

Proteostasis involves a highly complex interconnection of pathways that influence the fate of a protein from synthesis to degradation. As individual components are affected, the others adjust accordingly to maintain normal function. Disruption of one or more of these proteostasis influencers can manifest in pathologies such as Alzheimer’s disease, cancer, and diabetes.

To fuel your proteostatis research, Enzo Life Sciences has an unrivaled portfolio of ubiquitin/proteasome and heat shock protein research reagents through our acquistion of Biomol International and Stressgen® Bioreagents. Our development efforts within the areas of protein synthesis, modification, and degradation continue to produce cutting-edge tools for dissecting key biological processes at the forefront of academic discourse in the proteostasis field. This commitment is evidenced most recently by first-to-market immunoassays, cell based assays, and compound libraries for autophagy, an emerging pathway of interest in cellular regulation of protein turnover and its relation to disease.