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Granulocyte-colony stimulating factor (human), (recombinant)

 
ENZ-PRT215-0010 10 µg 300.00 USD
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Product Specification

Alternative Name:CSF-3, G-CSF, Pluripoietin, MGI-1G
 
MW:~ 18.8 kDa
 
Source:Produced in E. coli. A monomer containing 175 amino acids.
 
UniProt ID:P09919
 
Formulation:Lyophilized. Contains 0.1% trifluoroacetic acid.
 
Purity:≥95% (SDS-PAGE)
 
Endotoxin Content:≤ 1 EU/µg protein (LAL test)
 
Reconstitution:Reconstitute in sterile water at 0.1 mg/mL.
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-80°C
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
 
Scientific Background:Granulocyte-colony stimulating factor (G-CSF) is a growth factor that induces terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by endotoxins, TNF, IL-1 and GM-CSF. IL-17 can induce synthesis in epithelial, endothelial and fibroblastic cells. Prostaglandin E2 inhibits the G-CSF. Human and mouse G-CSF are cross-reactive.
 

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