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PDL2 monoclonal antibody (7C7)

 
ENZ-ABS697-0100 100 µg 457.00 USD
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Product Specification

Alternative Name:CD273, PDCD1L2, Programmed cell death 1 ligand 2, PD-1 ligand 2
 
Clone:7C7
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Extracellular domain of human PD-L2.
 
UniProt ID:P9BQ51
 
Species reactivity:Human
 
Applications:Flow Cytometry, ICC, IF, IHC (PS), WB
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored as recommended.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC).T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2, both of which are thought act as a negative regulator of T cell activation.
 

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