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Fibrinogen (human) monoclonal antibody (1D6)

 
BPD-HYB-051-04-02 200 µg 388.00 USD
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Product Specification

Alternative Name:fibrin precursor
 
Clone:1D6
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Human fibrinogen from plasma.
 
UniProt ID:P02671 (α chain), P02675 (β chain), P02679 (γ chain)
 
Species reactivity:Human
 
Applications:ELISA, WB
 
Application Notes:Detects a band of ~340kDa by Western blot.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Fibrinogen consists as a dimer of 3 pairs of non-identical chains, aa (Mr= 66,800), Bb (Mr= 52,000) and g (Mr=46,500), cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2-terminal D domains and one central E domain, with all three domains separated when fibrinogen is degradated by plasmin. The molecular weight is 340kDa. Concentration in human plasma is 2-3 mg/mL.
 

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