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Caspase-2 (human), (recombinant)

BML-SE175-5000 5000 U 424.00 USD
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Product Specification

MW:19 + 12 kDa
Source:Produced in E. coli. Human caspase-2 (aa 150-435)
UniProt ID:P42575
Concentration:100 U/µl
Formulation:Liquid. In 50mM HEPES, pH 7.4, 100mM NaCl, 0.1% CHAPS, 1mM EDTA, 10% glycerol and 10mM DTT.
Purity Detail:Partially purified by single-step affinity chromatography and gel filtration.
Specific Activity:One U=1pmol/min at 30°C using Ac-LEHD-pNA (200 µM; Prod. No. ALX-260-081) as substrate.
Shipping:Shipped on Dry Ice
Long Term Storage:-80°C
Scientific Background:The caspase-2 proenzyme includes a CARD (Caspase Recruitment Domain) in its long N-terminal prodomain. It can associate with the Tumor Necrosis Factor Receptor 1 in a complex comprising the adaptor proteins RAIDD (CRADD) and TRADD and RIP Kinase.

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For Research Use Only. Not for use in diagnostic procedures.
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