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β-Synuclein polyclonal antibody

 
BML-SA3405-0025 25 µl 100.00 USD
 
BML-SA3405-0100 100 µl 329.00 USD
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Product Specification

Alternative Name:PNP14, Phosphoneuroprotein 14, SNCB
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to aa 97-111 of human β-synuclein.
 
UniProt ID:Q16143
 
Species reactivity:Human, Mouse, Rat
 
Applications:IHC, WB
 
Blocking Peptide:For Blocking peptide see Prod. No. BML-SP9345.
 
Formulation:Liquid. In PBS, pH 7.4 containing 0.01M sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:β-synuclein (phosphoneuroprotein 14; SNCB) is abundant in the central nervous system and is localised at nerve endings but not in synaptic vesicles. β-synuclein is associated with novel axonal pathology in Parkinson’s disease and in dementia with Lewy bodies. Unlike a-synuclein in which two mutations associated with familial Parkinson's disease have been found, no pathogenic mutations have been identified in β-synuclein. β-synuclein expression in the testis changes with developmental stage, being increased markedly when spermatogonia undergo two rounds of meiosis, suggesting a role for β-synuclein in meiosis.
 

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