Kinase inhibitor library



BML-2832-0500	1 Library	500 µl/well	INQUIRE

BML-2832-0100	1 Library	100 µl/well	INQUIRE

The Screen-Well^TM Kinase Inhibitor Library contains 80 known kinase inhibitors of well-defined activity. Inhibitors are supplied dissolved in DMSO at 10 mM and aliquoted into deep-well plates at either 100 or 500 microliters per well. The library is an ideal tool for chemical genomics, assay development and other pharmacological applications. Includes inhibitors of these important kinases: Insulin/IGF Receptors, PI 3-Kinase, CaM Kinase II, JAK, PKA, CDK, JNK, PKC, CKI II, MAPK, RAF, EGFR, MEK, SAPK, GSK, MLCK, Src-family, IKK, PDGFR, VEGFR and many more.Contact compoundlibraries@enzolifesciences.com for a complete list of compounds in the library.

For details on the terms of use of this product, click here.

Product Specification

Concentration:	DMSO solutions (10mM)

Quantity:	100µl or 500µl per well

Kit/Set Contains:	80 compounds including inhibitors of these important kinases: BTK, CaM Kinase, CDK, CKI & II, EGFR, GSK, IKK, Insulin receptor, JAK, JNK, MAPK, MEK, MLCK, PI 3-Kinase, PDGFR, PKA, PKC, RAF, SAPK, Src-family, VEGFR, and more.

Long Term Storage:	-80°C

Background / Technical Information:	Please click here for the comprehensive product data sheet.

Product Literature References

Small molecule screening identifies targetable zebrafish pigmentation pathways: S. Colanesi, et al.; Pigment Cell Melanoma Res. Accepted as DOI: 10.1111/j.1755-148X.2012.00977.x, (2012), Abstract;

Amphotericin B, identified from a natural product screen, antagonizes CNS inhibitors to promote axon growth via activation of an Akt pathway in neurons: Y. Gao et al.; J. Neurochem. 113, 1331 (2010), Application, Abstract;

Cell treatment and lysis in 96-well filter-bottom plates for screening Bcr-Abl activity and inhibition in whole-cell extracts: M.R. Mand et al.; J. Biomol. Screen. 15, 434 (2010), Application, Abstract;

High content screening for inhibitors of protein interactions and post-translational modifications in primary cells by proximity ligation: K.J. Leuchowius et al.; Mol. Cell. Proteomics 9, 178 (2010), Application, Abstract;

A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation: J. P. Saxe; Chem. Biol. 14, 1019 (2007), Abstract;

High-content classification of nucleocytoplasmic import or export inhibitors: Y.-J. Kwon et al.; J. Biomol. Screen. 12, 621 (2007), Abstract;

A robust screen for inhibitors and enhancers of phosphoinositide-3 kinase (PI3K) activities by ratiometric fluorescence superquenching: C. Stankewicz et al.; J. Biomol. Screen . 11, 413 (2006), Abstract;

Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition: J. Trapp et al.; J. Med. Chem. 49, 7307 (2006), Abstract;

Biotinylated peptides for rapid identification of substrates and inhibitors of kinases and phosphatases with fluorescence superquenching : S. Wittenburg, et al.; Assay Drug Dev. Technol. 4, 535 (2006),

Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling: P. O. Krutzik; Nat. Methods. 3, 361 (2006), Abstract;

State-based discovery: a multidimensional screen for small-molecule modulators of EGF signaling: M. Sevecka et al.; Nat. Methods. 3, 825 (2006), Abstract;