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CD45RA (human) monoclonal antibody (MEM-56) (FITC conjugate)

 
ALX-805-067F-T100 100 tests FITC 240.00 USD
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Product Specification

Clone:MEM-56
 
Host:Mouse
 
Isotype:IgG2b
 
Immunogen:Human thymocytes and T lymphocytes.
 
UniProt ID:P08575
 
Species reactivity:Human
 
Applications:Flow Cytometry
 
Purity Detail:Protein A-affinity purified.
 
Formulation:Liquid. In PBS, pH 7.4, containing 0.2% BSA and 15mM sodium azide.
 
Handling:Do not freeze. Protect from light.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:+4°C
 
Scientific Background:Human CD45RA is expressed on all cells of hematopoietic origin, except erythrocytes. CD45RA is a transmembrane tyrosine phosphate which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing of exons 4-7 of a single gene coding for the various N-terminal peptide segments. The CD45RA isoform predominates on naive/resting T cells and medullary thymocytes.
 

Product Literature References

Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102: V. Bazil, et al.; Folia Biol (Praha) 35, 289 (1989), Abstract;
Sialic acid-dependent epitopes of CD45 molecules of restricted cellular expression: V. Bazil, et al.; Immunogenetics 29, 202 (1989), Abstract;

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