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Loperamide . hydrochloride

Ca2+ channel blocker
 
ALX-550-253-G005 5 g 49.00 USD
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Non-selective Ca2+ channel blocker. At nanomolar concentrations, binds to opioid μ-receptors. Does not cross the blood brain barrier.

Product Specification

Alternative Name:4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutyramide . HCl
 
Formula:C29H33ClN2O2 . HCl
 
MW:477.0 . 36.5
 
CAS:34552-83-5
 
MI:14: 5571
 
Purity:≥98% (HPLC)
 
Identity:Determined by 1H-NMR and LC-MS.
 
Appearance:White powder.
 
Solubility:Soluble in methanol or chloroform.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
ALX-550-253
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ALX-550-253

Product Literature References

Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects: I.J. Reynolds, et al.; J. Pharmacol. Exp. Ther. 231, 628 (1984), Abstract;

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