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CCR4 (human) polyclonal antibody

ALX-210-622-C200 200 µg 270.00 USD
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Product Specification

Alternative Name:C-C chemokine receptor 4, CD194
Immunogen:Synthetic peptide corresponding to aa 18-39 (S18NYYLYESIPK
PCTKEGIKAFGE39) of human CCR4 (C-C chemokine receptor 4).
UniProt ID:P51679
Species reactivity:Human
Applications:ICC, IHC (PS), WB
Recommended Dilutions/Conditions:Immunocytochemistry (acetone fixed cells, 1:400)
Immunohistochemistry (paraffin sections, 1:200)
Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Purity Detail:Epitope-affinity purified IgG.
Quality Control:Immunocytochemistry on mouse spleen cells.
Formulation:Liquid. In PBS containing 1mg/ml BSA and 0.1% sodium azide.
Handling:For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:Mouse CCR4 is the homolog of human CCR4 receptor (85% identical), binding macrophage inflammatory protein-1α (MIP-1α) and RANTES. Mouse CCR4 transcripts are expressed in the thymus and in T-cell lines.
Figure: Immunohistochemistry on paraffin sections of human spleen cells using PAb to CCR4 (human) (Prod No. ALX-210-622).
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General Literature References

Molecular cloning of murine CC CKR-4 and high affinity binding of chemokines to murine and human CC CKR-4: A. Hoogewerf, et al.; BBRC 218, 337 (1996), Abstract;

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For Research Use Only. Not for use in diagnostic procedures.
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