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p23 polyclonal antibody

 
ADI-SPA-670-D 50 µl 140.00 USD
 
ADI-SPA-670-F 200 µl 301.00 USD
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Product Specification

Alternative Name:Prostaglandin E synthase 3, HSP90 Co-chaperone
 
Host:Rabbit
 
Immunogen:Recombinant human p23.
 
UniProt ID:Q15185
 
Species reactivity:Human, Mouse, Rat
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~23kDa by Western blot.
 
Purity Detail:Antiserum.
 
Formulation:Serum.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:p23 is a ubiquitous, highly conserved co-chaperone for Hsp90 that participates in the folding of a number of cell regulatory proteins including progesterone and glucocorticoid receptors, HSF1, and telomerase. p23 is thought to modulate Hsp90 activity in the last stages of the chaperoning pathway by binding and stabilizing Hsp90 in its ATP-bound state.
 
SPA-670 WB
Western blot analysis of p23: Lane 1: MW, Lane 2: p23 (Prod. No. ADI-SPP-670), Lane 3: HeLa (Heat Shocked), Lane 4: mouse testes, and Lane 5: rat testes probed with p23, pAb (Prod. No. ADI-SPA-670).
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SPA-670 WB

Product Literature References

Psoriasis-associated variant Act1 D10N with impaired regulation by Hsp90: C. Wang, et al.; Nat. Immunol. 14, 72 (2013), Application(s): WB using MEF extracts, Abstract; Full Text

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Heat Shock Proteins & the Cellular Stress Response Catalog
Heat Shock Proteins & the Cellular Stress Response Catalog
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