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Acetylated Lysine polyclonal antibody (biotin conjugate)

 
ADI-KAP-TF1201B-E 100 µg 341.00 USD
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Product Specification

Alternative Name:AcK
 
Host:Rabbit
 
Immunogen:Acetylated KLH.
 
Species reactivity:Species independent
 
Applications:WB
 
Purity Detail:Immunoaffinity purified.
 
Formulation:Liquid. In PBS, pH 7.0, containing 50% glycerol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Acetylation and methylation of lysine are important post-translational modifications that regulate numerous protein-protein and protein-DNA interactions. Lysine acetylation and methylation involves the transfer of acetylCoA, or one or more methyl groups, to the e-amino group of lysine by modifying enzymes and cofactors. Histones and transcription factors are the primary targets of lysine acetylation and methylation, with either modification capable of inducing gene silencing or expression due to differential regulation of cofactors. For example, varying degrees of mono-, di-, and tri-methylation or acetylation of histone H3 at lysine residue 9 are known to demark distinct chromatin regions during various states of gene activation (methylation) or repression (acetylation).
 
KAP-TF1201B WB
Western blot analysis of the acetylated protein profile from TSA treated (left) and non-treated (right) human melanoma cell (MMRU) lysates .
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KAP-TF1201B WB

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