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c-Myc monoclonal antibody (1A6)

 
ADI-905-822-100 100 µl 410.00 USD
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Product Specification

Alternative Name:Myc proto-oncogene, Transcription factor p64
 
Clone:1A6
 
Host:Mouse
 
Isotype:IgG2b
 
Immunogen:Recombinant human full length c-Myc (aa 1-454).
 
UniProt ID:P01106
 
Species reactivity:Human
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1:2,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~51kDa (full length) by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
 
905-822 WB
Western blot analysis of HeLa cell lysate probed with c-Myc mAb (1A6) at 1:2000.
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905-822 WB

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